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Plant-Produced Asialo-Erythropoietin Restores Pancreatic Beta-Cell Function by Suppressing Mammalian Sterile-20-like Kinase (MST1) and Caspase-3 Activation
Pancreatic beta-cell death adversely contributes to the progression of both type I and II diabetes by undermining beta-cell mass and subsequently diminishing endogenous insulin production. Therapeutics to impede or even reverse the apoptosis and dysfunction of beta-cells are urgently needed. Asialo-...
Autores principales: | Arthur, Elena, Kittur, Farooqahmed S., Lin, Yuan, Hung, Chiu-Yueh, Sane, David C., Xie, Jiahua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395651/ https://www.ncbi.nlm.nih.gov/pubmed/28469576 http://dx.doi.org/10.3389/fphar.2017.00208 |
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