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Input Estimation for Extended-Release Formulations Exemplified with Exenatide

Estimating the in vivo absorption profile of a drug is essential when developing extended-release medications. Such estimates can be obtained by measuring plasma concentrations over time and inferring the absorption from a model of the drug’s pharmacokinetics. Of particular interest is to predict th...

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Detalles Bibliográficos
Autores principales:	Trägårdh, Magnus, Chappell, Michael J., Palm, Johan E., Evans, Neil D., Janzén, David L. I., Gennemark, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395652/ https://www.ncbi.nlm.nih.gov/pubmed/28470000 http://dx.doi.org/10.3389/fbioe.2017.00024

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