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Sedation levels in dogs: a validation study

BACKGROUND: The aim of this study was to assess validation evidence for a sedation scale for dogs. We hypothesized that the chosen sedation scale would be unreliable when used by different raters and show poor discrimination between sedation protocols. A sedation scale (range 0–21) was used to score...

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Autores principales: Wagner, Marika C., Hecker, Kent G., Pang, Daniel S. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395740/
https://www.ncbi.nlm.nih.gov/pubmed/28420386
http://dx.doi.org/10.1186/s12917-017-1027-2
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author Wagner, Marika C.
Hecker, Kent G.
Pang, Daniel S. J.
author_facet Wagner, Marika C.
Hecker, Kent G.
Pang, Daniel S. J.
author_sort Wagner, Marika C.
collection PubMed
description BACKGROUND: The aim of this study was to assess validation evidence for a sedation scale for dogs. We hypothesized that the chosen sedation scale would be unreliable when used by different raters and show poor discrimination between sedation protocols. A sedation scale (range 0–21) was used to score 62 dogs scheduled to receive sedation at two veterinary clinics in a prospective trial. Scores recorded by a single observer were used to assess internal consistency and construct validity of the scores. To assess inter-rater reliability, video-recordings of sedation assessment were randomized and blinded for viewing by 5 raters untrained in the scale. Videos were also edited to allow assessment of inter-rater reliability of an abbreviated scale (range 0–12) by 5 different raters. RESULTS: Both sedation scales exhibited excellent internal consistency and very good inter-rater reliability (full scale, intraclass correlation coefficient [ICC(single)] = 0.95; abbreviated scale, ICC(single) = 0.94). The full scale discriminated between the most common protocols: dexmedetomidine-hydromorphone (median [range] of sedation score, 11 [1–18], n = 20) and acepromazine-hydromorphone (5 [0–15], n = 36, p = 0.02). CONCLUSIONS: The hypothesis was rejected. Full and abbreviated scales showed excellent internal consistency and very good reliability between multiple untrained raters. The full scale differentiated between levels of sedation. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12917-017-1027-2) contains supplementary material, which is available to authorized users.
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spelling pubmed-53957402017-04-20 Sedation levels in dogs: a validation study Wagner, Marika C. Hecker, Kent G. Pang, Daniel S. J. BMC Vet Res Research Article BACKGROUND: The aim of this study was to assess validation evidence for a sedation scale for dogs. We hypothesized that the chosen sedation scale would be unreliable when used by different raters and show poor discrimination between sedation protocols. A sedation scale (range 0–21) was used to score 62 dogs scheduled to receive sedation at two veterinary clinics in a prospective trial. Scores recorded by a single observer were used to assess internal consistency and construct validity of the scores. To assess inter-rater reliability, video-recordings of sedation assessment were randomized and blinded for viewing by 5 raters untrained in the scale. Videos were also edited to allow assessment of inter-rater reliability of an abbreviated scale (range 0–12) by 5 different raters. RESULTS: Both sedation scales exhibited excellent internal consistency and very good inter-rater reliability (full scale, intraclass correlation coefficient [ICC(single)] = 0.95; abbreviated scale, ICC(single) = 0.94). The full scale discriminated between the most common protocols: dexmedetomidine-hydromorphone (median [range] of sedation score, 11 [1–18], n = 20) and acepromazine-hydromorphone (5 [0–15], n = 36, p = 0.02). CONCLUSIONS: The hypothesis was rejected. Full and abbreviated scales showed excellent internal consistency and very good reliability between multiple untrained raters. The full scale differentiated between levels of sedation. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12917-017-1027-2) contains supplementary material, which is available to authorized users. BioMed Central 2017-04-18 /pmc/articles/PMC5395740/ /pubmed/28420386 http://dx.doi.org/10.1186/s12917-017-1027-2 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Wagner, Marika C.
Hecker, Kent G.
Pang, Daniel S. J.
Sedation levels in dogs: a validation study
title Sedation levels in dogs: a validation study
title_full Sedation levels in dogs: a validation study
title_fullStr Sedation levels in dogs: a validation study
title_full_unstemmed Sedation levels in dogs: a validation study
title_short Sedation levels in dogs: a validation study
title_sort sedation levels in dogs: a validation study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395740/
https://www.ncbi.nlm.nih.gov/pubmed/28420386
http://dx.doi.org/10.1186/s12917-017-1027-2
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