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Neuroprotective effect of Demethoxycurcumin, a natural derivative of Curcumin on rotenone induced neurotoxicity in SH-SY 5Y Neuroblastoma cells
BACKGROUND: Mitochondrial dysfunction and oxidative stress are the main toxic events leading to dopaminergic neuronal death in Parkinson’s disease (PD) and identified as vital objective for therapeutic intercession. This study investigated the neuro-protective effects of the demethoxycurcumin (DMC),...
Autores principales: | Ramkumar, Muthu, Rajasankar, Srinivasagam, Gobi, Veerappan Venkatesh, Dhanalakshmi, Chinnasamy, Manivasagam, Thamilarasan, Justin Thenmozhi, Arokiasamy, Essa, Musthafa Mohamed, Kalandar, Ameer, Chidambaram, Ranganathan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395846/ https://www.ncbi.nlm.nih.gov/pubmed/28420370 http://dx.doi.org/10.1186/s12906-017-1720-5 |
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