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Genetic sequence-based prediction of long-range chromatin interactions suggests a potential role of short tandem repeat sequences in genome organization

BACKGROUND: Knowing the three-dimensional (3D) structure of the chromatin is important for obtaining a complete picture of the regulatory landscape. Changes in the 3D structure have been implicated in diseases. While there exist approaches that attempt to predict the long-range chromatin interaction...

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Detalles Bibliográficos
Autores principales: Nikumbh, Sarvesh, Pfeifer, Nico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395875/
https://www.ncbi.nlm.nih.gov/pubmed/28420341
http://dx.doi.org/10.1186/s12859-017-1624-x