Cargando…

Integrated genomic analysis of mitochondrial RNA processing in human cancers

BACKGROUND: The mitochondrial genome is transcribed as continuous polycistrons of RNA containing multiple genes. As a consequence, post-transcriptional events are critical for the regulation of gene expression and therefore all aspects of mitochondrial function. One particularly important process is...

Descripción completa

Detalles Bibliográficos
Autores principales:	Idaghdour, Youssef, Hodgkinson, Alan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395977/ https://www.ncbi.nlm.nih.gov/pubmed/28420414 http://dx.doi.org/10.1186/s13073-017-0426-0

Ejemplares similares

Analysis of mitochondrial m1A/G RNA modification reveals links to nuclear genetic variants and associated disease processes
por: Ali, Aminah Tasnim, et al.
Publicado: (2020)

Identification of human mitochondrial RNA cleavage sites and candidate RNA processing factors
por: Carbajosa, Guillermo, et al.
Publicado: (2022)

Selective constraint, background selection, and mutation accumulation variability within and between human populations
por: Hodgkinson, Alan, et al.
Publicado: (2013)

Falcon genomics in the context of conservation, speciation, and human culture
por: Wilcox, Justin J. S., et al.
Publicado: (2019)

A Genome-Wide Gene Expression Signature of Environmental Geography in Leukocytes of Moroccan Amazighs
por: Idaghdour, Youssef, et al.
Publicado: (2008)

Exploiting Gene Expression Variation to Capture Gene-Environment Interactions for Disease
por: Idaghdour, Youssef, et al.
Publicado: (2013)

Linked-Read Sequencing of Eight Falcons Reveals a Unique Genomic Architecture in Flux
por: Wilcox, Justin J S, et al.
Publicado: (2022)

Human Mitochondrial RNA Processing and Modifications: Overview
por: Jedynak-Slyvka, Marta, et al.
Publicado: (2021)

Integrative genomic analysis reveals mechanisms of immune evasion in P. falciparum malaria
por: Dieng, Mame Massar, et al.
Publicado: (2020)

Drosophila mitochondrial topoisomerase III alpha affects the aging process via maintenance of mitochondrial function and genome integrity
por: Tsai, Han-Zen, et al.
Publicado: (2016)

Mitochondrial Polyadenylation Is a One-Step Process Required for mRNA Integrity and tRNA Maturation
por: Bratic, Ana, et al.
Publicado: (2016)

Epigenetic therapy of acute myeloid leukemia using 5-aza-2'-deoxycytidine (decitabine) in combination with inhibitors of histone methylation and deacetylation
por: Momparler, Richard L, et al.
Publicado: (2014)

Modeling the integration of bacterial rRNA fragments into the human cancer genome
por: Sieber, Karsten B., et al.
Publicado: (2016)

The Genomic Distribution and Local Context of Coincident SNPs in Human and Chimpanzee
por: Hodgkinson, Alan, et al.
Publicado: (2010)

Nuclear genetic regulation of the human mitochondrial transcriptome
por: Ali, Aminah T, et al.
Publicado: (2019)

Structural basis of RNA processing by human mitochondrial RNase P
por: Bhatta, Arjun, et al.
Publicado: (2021)

Geographical Genomics of Human Leukocyte Gene Expression Variation in Southern Morocco
por: Idaghdour, Youssef, et al.
Publicado: (2009)

Nuclear and mitochondrial tRNA-lookalikes in the human genome
por: Telonis, Aristeidis G., et al.
Publicado: (2014)

Integrated analysis of RNA-binding proteins in human colorectal cancer
por: Fan, Xuehui, et al.
Publicado: (2020)

Mitochondrial RNA processing in absence of tRNA punctuations in octocorals
por: Shimpi, Gaurav G., et al.
Publicado: (2017)

Data on the time of integration of the human mitochondrial pseudogenes (NUMTs) into the nuclear genome
por: Gunbin, Konstantin, et al.
Publicado: (2017)

Inhibition of DNA and Histone Methylation by 5-Aza-2′-Deoxycytidine (Decitabine) and 3-Deazaneplanocin-A on Antineoplastic Action and Gene Expression in Myeloid Leukemic Cells
por: Momparler, Richard L., et al.
Publicado: (2017)

MitoMiner, an Integrated Database for the Storage and Analysis of Mitochondrial Proteomics Data
por: Smith, Anthony C., et al.
Publicado: (2009)

An integrative genomic analysis revealed the relevance of microRNA and gene expression for drug-resistance in human breast cancer cells
por: Yamamoto, Yusuke, et al.
Publicado: (2011)

Gene-by-environment interactions in urban populations modulate risk phenotypes
por: Favé, Marie-Julie, et al.
Publicado: (2018)

Integrative Analysis of Somatic Mutations Altering MicroRNA Targeting in Cancer Genomes
por: Ziebarth, Jesse D., et al.
Publicado: (2012)

Comparative Analysis of Iron Homeostasis in Sub-Saharan African Children with Sickle Cell Disease and Their Unaffected Siblings
por: Gomez, Selma, et al.
Publicado: (2016)

Hyperglycemic conditions induce rapid cell dysfunction-promoting transcriptional alterations in human aortic endothelial cells
por: Bayaraa, Odmaa, et al.
Publicado: (2022)

SePIA: RNA and small RNA sequence processing, integration, and analysis
por: Icay, Katherine, et al.
Publicado: (2016)

Integrative analyses of proteomics and RNA transcriptomics implicate mitochondrial processes, protein folding pathways and GWAS loci in Parkinson disease
por: Dumitriu, Alexandra, et al.
Publicado: (2016)

Genome-wide analysis of HPV integration in human cancers reveals recurrent, focal genomic instability
por: Akagi, Keiko, et al.
Publicado: (2014)

GRSF1 Regulates RNA Processing in Mitochondrial RNA Granules
por: Jourdain, Alexis A., et al.
Publicado: (2013)

Integrative Analysis of the Mitochondrial Proteome in Yeast
por: Prokisch, Holger, et al.
Publicado: (2004)

Structure of human mitochondrial RNA polymerase elongation complex
por: Schwinghammer, Kathrin, et al.
Publicado: (2013)

Integrated Functional, Gene Expression and Genomic Analysis for the Identification of Cancer Targets
por: Iorns, Elizabeth, et al.
Publicado: (2009)

The FASTK family proteins fine-tune mitochondrial RNA processing
por: Ohkubo, Akira, et al.
Publicado: (2021)

Addressing RNA Integrity to Determine the Impact of Mitochondrial DNA Mutations on Brain Mitochondrial Function with Age
por: Wang, Wei, et al.
Publicado: (2014)

The Mitochondrial Genome Is a “Genetic Sanctuary” during the Oncogenic Process
por: Seoane, Marcos, et al.
Publicado: (2011)

MicroRNA Processing and Human Cancer
por: Ohtsuka, Masahisa, et al.
Publicado: (2015)

Comprehensive molecular characterization of mitochondrial genomes in human cancers
por: Yuan, Yuan, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_of47fnc8ko9m0r4bj782ocsd53