Pirfenidone attenuates bleomycin-induced pulmonary fibrosis in mice by regulating Nrf2/Bach1 equilibrium

BACKGROUND: Oxidative stress is one of the important factors involved in the pathogenesis of idiopathic pulmonary fibrosis (IPF). The equilibrium of Nuclear factor-erythroid-related factor 2 (Nrf2)/[BTB (broad-complex, tramtrack and bric-a-brac) and CNC (cap‘n’collar protein) homology 1, Bach1] dete...

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Detalles Bibliográficos
Autores principales: Liu, Yuan, Lu, Fuai, Kang, Lirong, Wang, Zhihua, Wang, Yongfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395978/
https://www.ncbi.nlm.nih.gov/pubmed/28420366
http://dx.doi.org/10.1186/s12890-017-0405-7

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