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Esophageal squamous papilloma lacks clear clinicopathological associations

AIM: To determine the prevalence of esophageal squamous papillomas (ESPs) in a tertiary teaching hospital and to assess for any clinical associations, including relations with esophageal squamous cell carcinomas (SCCs). METHODS: Data from a total of 6962 upper gastrointestinal endoscopies over a fiv...

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Autores principales: Jideh, Bilel, Weltman, Martin, Wu, Yang, Chan, Calvin H Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395981/
https://www.ncbi.nlm.nih.gov/pubmed/28470005
http://dx.doi.org/10.12998/wjcc.v5.i4.134
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author Jideh, Bilel
Weltman, Martin
Wu, Yang
Chan, Calvin H Y
author_facet Jideh, Bilel
Weltman, Martin
Wu, Yang
Chan, Calvin H Y
author_sort Jideh, Bilel
collection PubMed
description AIM: To determine the prevalence of esophageal squamous papillomas (ESPs) in a tertiary teaching hospital and to assess for any clinical associations, including relations with esophageal squamous cell carcinomas (SCCs). METHODS: Data from a total of 6962 upper gastrointestinal endoscopies over a five year period were retrospectively obtained and analysed. RESULTS: ESP was found in sixteen patients (0.23%). Eight (50%) patients had a high body mass index, seven (44%) had history of cigarette smoking. Reflux esophagitis was found in four (25%) patients. All ESPs were solitary with a mean endoscopic size of 3.8 mm and located in the mid to lower esophagus. Human papilloma virus (HPV) was tested in three (19%) patients and was negative. Esophageal SCC was found in seven patients (0.10%) during the same period. None of the specimens were tested for HPV, and none had associated papillomatous changes. CONCLUSION: ESP is an uncommon tumour with unclear clinical associations and malignant potential.
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spelling pubmed-53959812017-05-03 Esophageal squamous papilloma lacks clear clinicopathological associations Jideh, Bilel Weltman, Martin Wu, Yang Chan, Calvin H Y World J Clin Cases Retrospective Study AIM: To determine the prevalence of esophageal squamous papillomas (ESPs) in a tertiary teaching hospital and to assess for any clinical associations, including relations with esophageal squamous cell carcinomas (SCCs). METHODS: Data from a total of 6962 upper gastrointestinal endoscopies over a five year period were retrospectively obtained and analysed. RESULTS: ESP was found in sixteen patients (0.23%). Eight (50%) patients had a high body mass index, seven (44%) had history of cigarette smoking. Reflux esophagitis was found in four (25%) patients. All ESPs were solitary with a mean endoscopic size of 3.8 mm and located in the mid to lower esophagus. Human papilloma virus (HPV) was tested in three (19%) patients and was negative. Esophageal SCC was found in seven patients (0.10%) during the same period. None of the specimens were tested for HPV, and none had associated papillomatous changes. CONCLUSION: ESP is an uncommon tumour with unclear clinical associations and malignant potential. Baishideng Publishing Group Inc 2017-04-16 2017-04-16 /pmc/articles/PMC5395981/ /pubmed/28470005 http://dx.doi.org/10.12998/wjcc.v5.i4.134 Text en ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.
spellingShingle Retrospective Study
Jideh, Bilel
Weltman, Martin
Wu, Yang
Chan, Calvin H Y
Esophageal squamous papilloma lacks clear clinicopathological associations
title Esophageal squamous papilloma lacks clear clinicopathological associations
title_full Esophageal squamous papilloma lacks clear clinicopathological associations
title_fullStr Esophageal squamous papilloma lacks clear clinicopathological associations
title_full_unstemmed Esophageal squamous papilloma lacks clear clinicopathological associations
title_short Esophageal squamous papilloma lacks clear clinicopathological associations
title_sort esophageal squamous papilloma lacks clear clinicopathological associations
topic Retrospective Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395981/
https://www.ncbi.nlm.nih.gov/pubmed/28470005
http://dx.doi.org/10.12998/wjcc.v5.i4.134
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