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Tumor Microenvironment Activable Self‐Assembled DNA Hybrids for pH and Redox Dual‐Responsive Chemotherapy/PDT Treatment of Hepatocellular Carcinoma

Smart self‐assembled “Turn‐ON” DNA hybrids are employed, which could respond to tumor microenvironment stimuli for cancer cell specific real‐time fluorescence imaging, tumor‐specific synergistic photodynamic therapy and chemotherapy in hepatocellular carcinoma. [Image: see text]

Detalles Bibliográficos
Autores principales: Zhang, Da, Zheng, Aixian, Li, Juan, Wu, Ming, Cai, Zhixiong, Wu, Lingjie, Wei, Zuwu, Yang, Huanghao, Liu, Xiaolong, Liu, Jingfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396159/
https://www.ncbi.nlm.nih.gov/pubmed/28435778
http://dx.doi.org/10.1002/advs.201600460
Descripción
Sumario:Smart self‐assembled “Turn‐ON” DNA hybrids are employed, which could respond to tumor microenvironment stimuli for cancer cell specific real‐time fluorescence imaging, tumor‐specific synergistic photodynamic therapy and chemotherapy in hepatocellular carcinoma. [Image: see text]