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Neural Imaging Using Single-Photon Avalanche Diodes
INTRODUCTION: This paper analyses the ability of single-photon avalanche diodes (SPADs) for neural imaging. The current trend in the production of SPADs moves toward the minimum dark count rate (DCR) and maximum photon detection probability (PDP). Moreover, the jitter response which is the main meas...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Iranian Neuroscience Society
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396169/ https://www.ncbi.nlm.nih.gov/pubmed/28446946 http://dx.doi.org/10.15412/J.BCN.03080103 |
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author | Karami, Mohammad Azim Ansarian, Misagh |
author_facet | Karami, Mohammad Azim Ansarian, Misagh |
author_sort | Karami, Mohammad Azim |
collection | PubMed |
description | INTRODUCTION: This paper analyses the ability of single-photon avalanche diodes (SPADs) for neural imaging. The current trend in the production of SPADs moves toward the minimum dark count rate (DCR) and maximum photon detection probability (PDP). Moreover, the jitter response which is the main measurement characteristic for the timing uncertainty is progressing. METHODS: The neural imaging process using SPADs can be performed by means of florescence lifetime imaging (FLIM), time correlated single-photon counting (TCSPC), positron emission tomography (PET), and single-photon emission computed tomography (SPECT). RESULTS: This trend will result in more precise neural imaging cameras. While achieving low DCR SPADs is difficult in deep submicron technologies because of using higher doping profiles, higher PDPs are reported in green and blue part of light. Furthermore, the number of pixels integrated in the same chip is increasing with the technology progress which can result in the higher resolution of imaging. CONCLUSION: This study proposes implemented SPADs in Deep-submicron technologies to be used in neural imaging cameras, due to the small size pixels and higher timing accuracies. |
format | Online Article Text |
id | pubmed-5396169 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Iranian Neuroscience Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-53961692017-04-26 Neural Imaging Using Single-Photon Avalanche Diodes Karami, Mohammad Azim Ansarian, Misagh Basic Clin Neurosci Research Papers INTRODUCTION: This paper analyses the ability of single-photon avalanche diodes (SPADs) for neural imaging. The current trend in the production of SPADs moves toward the minimum dark count rate (DCR) and maximum photon detection probability (PDP). Moreover, the jitter response which is the main measurement characteristic for the timing uncertainty is progressing. METHODS: The neural imaging process using SPADs can be performed by means of florescence lifetime imaging (FLIM), time correlated single-photon counting (TCSPC), positron emission tomography (PET), and single-photon emission computed tomography (SPECT). RESULTS: This trend will result in more precise neural imaging cameras. While achieving low DCR SPADs is difficult in deep submicron technologies because of using higher doping profiles, higher PDPs are reported in green and blue part of light. Furthermore, the number of pixels integrated in the same chip is increasing with the technology progress which can result in the higher resolution of imaging. CONCLUSION: This study proposes implemented SPADs in Deep-submicron technologies to be used in neural imaging cameras, due to the small size pixels and higher timing accuracies. Iranian Neuroscience Society 2017-01 /pmc/articles/PMC5396169/ /pubmed/28446946 http://dx.doi.org/10.15412/J.BCN.03080103 Text en Copyright© 2017 Iranian Neuroscience Society http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Papers Karami, Mohammad Azim Ansarian, Misagh Neural Imaging Using Single-Photon Avalanche Diodes |
title | Neural Imaging Using Single-Photon Avalanche Diodes |
title_full | Neural Imaging Using Single-Photon Avalanche Diodes |
title_fullStr | Neural Imaging Using Single-Photon Avalanche Diodes |
title_full_unstemmed | Neural Imaging Using Single-Photon Avalanche Diodes |
title_short | Neural Imaging Using Single-Photon Avalanche Diodes |
title_sort | neural imaging using single-photon avalanche diodes |
topic | Research Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396169/ https://www.ncbi.nlm.nih.gov/pubmed/28446946 http://dx.doi.org/10.15412/J.BCN.03080103 |
work_keys_str_mv | AT karamimohammadazim neuralimagingusingsinglephotonavalanchediodes AT ansarianmisagh neuralimagingusingsinglephotonavalanchediodes |