Cargando…

Protodioscin, Isolated from the Rhizome of Dioscorea tokoro Collected in Northern Japan is the Major Antiproliferative Compound to HL-60  Leukemic Cells

Abstract: Background: The rhizome of Oni-dokoro (a wild yam, Dioscorea tokoro) has extremely bitter taste and is not generally regarded edible;, however, in northern part of Japan, such as Iwate and a part of Aomori, it is used as health promoting food. To clarify the reason, we examined the biologi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Oyama, Manami, Tokiwano, Tetsuo, Kawaii, Satoru, Yoshida, Yasunori, Mizuno, Kouichi, Oh, Keimei, Yoshizawa, Yuko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bentham Science Publishers 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396219/ https://www.ncbi.nlm.nih.gov/pubmed/28579930 http://dx.doi.org/10.2174/1573407213666170113123428

Ejemplares similares

Steroidal Saponins Isolated from the Rhizome of Dioscorea tokoro Inhibit Cell Growth and Autophagy in Hepatocellular Carcinoma Cells
por: Okubo, Shinya, et al.
Publicado: (2021)

pH homeostasis in promyelocytic leukemic HL60 cells
Publicado: (1988)

Immunocytochemistry of Apoptosis Induced by Bromodeoxyuridine in Human Leukemic HL‐60 Cells
por: Kondo, Kazumasa, et al.
Publicado: (1997)

Antiproliferative effect of ZSTK474 alone or in combination with chemotherapeutic drugs on HL60 and HL60/ADR cells
por: Zhou, Qianxiang, et al.
Publicado: (2017)

Content of the Saponin Protodioscin in Brachiaria spp. from the Eastern Plains of Colombia
por: Lozano, Maria C., et al.
Publicado: (2017)

Immunomodulatory activity of Dioscorea membranacea Pierre rhizomes and of its main active constituent Dioscorealide B
por: Panthong, Sumalee, et al.
Publicado: (2014)

Comparison of Structural and Functional Properties of Starches from the Rhizome and Bulbil of Chinese Yam (Dioscorea opposita Thunb.)
por: Zhang, Biao, et al.
Publicado: (2018)

Natural Compound Methyl Protodioscin Suppresses Proliferation and Inhibits Glycolysis in Pancreatic Cancer
por: Chen, LianYu, et al.
Publicado: (2018)

Transcriptome analysis of Asparagus officinalis reveals genes involved in the biosynthesis of rutin and protodioscin
por: Yi, Tae Gyu, et al.
Publicado: (2019)

Antifungal Effects of Saponin Extract from Rhizomes of Dioscorea panthaica Prain et Burk against Candida albicans
por: Yang, Longfei, et al.
Publicado: (2018)

Additional Benefit of Chinese Medicine Formulae Including Dioscoreae rhizome (Shanyao) for Diabetes Mellitus: Current State of Evidence
por: Sun, Lu, et al.
Publicado: (2020)

In vitro evaluation of dioscin and protodioscin against ER-positive and triple-negative breast cancer
por: Bouchmaa, Najat, et al.
Publicado: (2023)

Functional changes in human leukemic cell line HL-60. A model for myeloid differentiation
por: Newburger, PE, et al.
Publicado: (1979)

Antileukemic Potential of Momordica charantia Seed Extracts on Human Myeloid Leukemic HL60 Cells
por: Soundararajan, Ramani, et al.
Publicado: (2012)

Retinoic Acid Therapy Resistance Progresses from Unilineage to Bilineage in HL-60 Leukemic Blasts
por: Jensen, Holly A., et al.
Publicado: (2014)

HOXB1 restored expression promotes apoptosis and differentiation in the HL60 leukemic cell line
por: Petrini, Marina, et al.
Publicado: (2013)

Anti-Leukemic Activity of Brassica-Derived Bioactive Compounds in HL-60 Myeloid Leukemia Cells
por: Núñez-Sánchez, María Ángeles, et al.
Publicado: (2022)

Antiproliferative Effect of Solanum nigrum on Human Leukemic Cell Lines
por: Gabrani, Reema, et al.
Publicado: (2012)

Methyl Protodioscin from the Roots of Asparagus cochinchinensis Attenuates Airway Inflammation by Inhibiting Cytokine Production
por: Lee, Ju Hee, et al.
Publicado: (2015)

Radiosensitization of Human Leukemic HL-60 Cells by ATR Kinase Inhibitor (VE-821): Phosphoproteomic Analysis
por: Šalovská, Barbora, et al.
Publicado: (2014)

The Effects of Purified Artemia Extract Proteins on Proliferation, Differentiation and Apoptosis of Human Leukemic HL-60 Cells
por: Deezagi, Abdolkhaleg, et al.
Publicado: (2016)

Immunomodulatory Effects of Dioscoreae Rhizome Against Inflammation through Suppressed Production of Cytokines Via Inhibition of the NF-κB Pathway
por: Kim, Seulah, et al.
Publicado: (2012)

Dioscorea nipponica Makino Rhizome Extract and Its Active Compound Dioscin Protect against Neuroinflammation and Scopolamine-Induced Memory Deficits
por: Azam, Shofiul, et al.
Publicado: (2022)

In Vitro Morphological Assessment of Apoptosis Induced by Antiproliferative Constituents from the Rhizomes of Curcuma zedoaria
por: Syed Abdul Rahman, Syarifah Nur, et al.
Publicado: (2013)

Cytotoxic and Antiproliferative Effects of Diarylheptanoids Isolated from Curcuma comosa Rhizomes on Leukaemic Cells
por: Viriyaadhammaa, Natsima, et al.
Publicado: (2020)

Natural compound methyl protodioscin protects against intestinal inflammation through modulation of intestinal immune responses
por: Zhang, Rongli, et al.
Publicado: (2015)

The Steroid Saponin Protodioscin Modulates Arabidopsis thaliana Root Morphology Altering Auxin Homeostasis, Transport and Distribution
por: Santos Wagner, Ana Luiza, et al.
Publicado: (2021)

Glycyrrhetinic Acid Induces Apoptosis in Leukemic HL60 Cells Through Upregulating of CD95/ CD178
por: Pirzadeh, Sara, et al.
Publicado: (2014)

Secondary Metabolites, Antioxidant, and Antiproliferative Activities of Dioscorea bulbifera Leaf Collected from Endau Rompin, Johor, Malaysia
por: Mainasara, Muhammad Murtala, et al.
Publicado: (2021)

Activation of PKC-ε counteracts maturation and apoptosis of HL-60 myeloid leukemic cells in response to TNF family members
por: Gonelli, A., et al.
Publicado: (2009)

Activation of NQO1 in NQO1*2 polymorphic human leukemic HL-60 cells by diet-derived sulforaphane
por: Wu, Joseph M., et al.
Publicado: (2016)

Investigation of the Antiproliferative Properties of Natural Sesquiterpenes from Artemisia asiatica and Onopordum acanthium on HL-60 Cells in Vitro
por: Molnár, Judit, et al.
Publicado: (2016)

Antiproliferative Properties of Papaver rhoeas Ovule Extracts and Derived Fractions Tested on HL60 Leukemia Human Cells
por: Ovidi, Elisa, et al.
Publicado: (2020)

Dihydroisocoumarins and Dihydroisoflavones from the Rhizomes of Dioscorea collettii with Cytotoxic Activity and Structural Revision of 2,2′-Oxybis(1,4-di-tert-butylbenzene)
por: Jing, Songsong, et al.
Publicado: (2021)

Induction of hypoxia-inducible factor-1α inhibits drug-induced apoptosis in the human leukemic cell line HL-60
por: Yook, Yeon-Joo, et al.
Publicado: (2010)

A comparative study of anti-leukemic effects of kaempferol and epigallocatechin-3-gallate (EGCG) on human leukemia HL-60 cells
por: Jokar, Mohammad Hassan, et al.
Publicado: (2021)

Mitophagy Effects of Protodioscin on Human Osteosarcoma Cells by Inhibition of p38MAPK Targeting NIX/LC3 Axis
por: Huang, Chien-Feng, et al.
Publicado: (2023)

Protodioscin protects porcine oocytes against H(2)O(2)-induced oxidative stress during in vitro maturation
por: Kim, So-Hee, et al.
Publicado: (2023)

Effects of Rhizome Extract of Dioscorea batatas and Its Active Compound, Allantoin, on the Regulation of Myoblast Differentiation and Mitochondrial Biogenesis in C2C12 Myotubes
por: Ma, Junnan, et al.
Publicado: (2018)

Platyphylloside Isolated from Betula platyphylla is Antiproliferative and Induces Apoptosis in Colon Cancer and Leukemic Cells
por: Lee, Joo-Eun, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_nt8tp5a7ulgrvkd06pri789qfp