An enhanced recombinant amino‐terminal acetylation system and novel in vivo high‐throughput screen for molecules affecting α‐synuclein oligomerisation

Amino‐terminal acetylation is a ubiquitous protein modification affecting the majority of eukaryote proteins to regulate stability and function. We describe an optimised recombinant expression system for rapid production of amino terminal‐acetylated proteins within bacteria. We go on to describe the...

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Detalles Bibliográficos
Autores principales: Eastwood, Tara A., Baker, Karen, Brooker, Holly R., Frank, Stefanie, Mulvihill, Daniel P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Letters
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396276/
https://www.ncbi.nlm.nih.gov/pubmed/28214355
http://dx.doi.org/10.1002/1873-3468.12597

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396276/
https://www.ncbi.nlm.nih.gov/pubmed/28214355
http://dx.doi.org/10.1002/1873-3468.12597

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