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Open‐label, proof‐of‐concept study of brexanolone in the treatment of severe postpartum depression
OBJECTIVE: Preclinical evidence indicates that rapid changes in levels of allopregnanolone, the predominant metabolite of progesterone, confer dramatic behavioral changes and may trigger postpartum depression (PPD) in some women. Considering the pathophysiology of PPD (i.e., triggered by reproductiv...
Autores principales: | Kanes, Stephen J., Colquhoun, Helen, Doherty, James, Raines, Shane, Hoffmann, Ethan, Rubinow, David R., Meltzer‐Brody, Samantha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396368/ https://www.ncbi.nlm.nih.gov/pubmed/28370307 http://dx.doi.org/10.1002/hup.2576 |
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