Liver X Receptor Agonist TO901317 Attenuates Paraquat-Induced Acute Lung Injury through Inhibition of NF-κB and JNK/p38 MAPK Signal Pathways

Paraquat (PQ) is a widely used herbicide with extremely high poisoning mortality mostly from acute lung injury (ALI) or progressive pulmonary fibrosis. Toxicity mechanisms remain unclear, but a redox cycling process that generates reactive oxygen species (ROS) is involved, as are inflammation and ce...

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Detalles Bibliográficos
Autores principales: Hu, Xiao, Shen, Haitao, Wang, Yu, Zhao, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396433/
https://www.ncbi.nlm.nih.gov/pubmed/28480221
http://dx.doi.org/10.1155/2017/4652695

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396433/
https://www.ncbi.nlm.nih.gov/pubmed/28480221
http://dx.doi.org/10.1155/2017/4652695

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