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Catestatin and orexin-A influence hamster thermic states during hibernation

Decreased body temperature during hibernation evokes a neuroprotective effect against the frequent neurodegenerative events of ischemic/reperfusion injuries. This neuroprotection appears to stem from a direct involvement of orexin-A plus the sympathoinhibitory neuroactive peptide catestatin on orexi...

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Detalles Bibliográficos
Autores principales: Mele, Maria, Canonaco, Marcello
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396516/
https://www.ncbi.nlm.nih.gov/pubmed/28439529
http://dx.doi.org/10.4161/temp.29547
Descripción
Sumario:Decreased body temperature during hibernation evokes a neuroprotective effect against the frequent neurodegenerative events of ischemic/reperfusion injuries. This neuroprotection appears to stem from a direct involvement of orexin-A plus the sympathoinhibitory neuroactive peptide catestatin on orexin 2 receptor-dependent feeding and motor behaviors of the facultative hibernating hamster.