Steroid metabolome analysis reveals prevalent glucocorticoid excess in primary aldosteronism

BACKGROUND. Adrenal aldosterone excess is the most common cause of secondary hypertension and is associated with increased cardiovascular morbidity. However, adverse metabolic risk in primary aldosteronism extends beyond hypertension, with increased rates of insulin resistance, type 2 diabetes, and...

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Detalles Bibliográficos
Autores principales: Arlt, Wiebke, Lang, Katharina, Sitch, Alice J., Dietz, Anna S., Rhayem, Yara, Bancos, Irina, Feuchtinger, Annette, Chortis, Vasileios, Gilligan, Lorna C., Ludwig, Philippe, Riester, Anna, Asbach, Evelyn, Hughes, Beverly A., O’Neil, Donna M., Bidlingmaier, Martin, Tomlinson, Jeremy W., Hassan-Smith, Zaki K., Rees, D. Aled, Adolf, Christian, Hahner, Stefanie, Quinkler, Marcus, Dekkers, Tanja, Deinum, Jaap, Biehl, Michael, Keevil, Brian G., Shackleton, Cedric H.L., Deeks, Jonathan J., Walch, Axel K., Beuschlein, Felix, Reincke, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2017
Materias:
Clinical Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396526/
https://www.ncbi.nlm.nih.gov/pubmed/28422753
http://dx.doi.org/10.1172/jci.insight.93136

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