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Auxotonic to isometric contraction transitioning in a beating heart causes myosin step-size to down shift

Myosin motors in cardiac ventriculum convert ATP free energy to the work of moving blood volume under pressure. The actin bound motor cyclically rotates its lever-arm/light-chain complex linking motor generated torque to the myosin filament backbone and translating actin against resisting force. Pre...

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Detalles Bibliográficos
Autores principales: Burghardt, Thomas P., Sun, Xiaojing, Wang, Yihua, Ajtai, Katalin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396871/
https://www.ncbi.nlm.nih.gov/pubmed/28423017
http://dx.doi.org/10.1371/journal.pone.0174690

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