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Targeted delivery of thymosin beta 4 to the injured myocardium using CREKA-conjugated nanoparticles
PURPOSE: Thymosin beta 4 (Tβ4) has multiple beneficial facets for myocardial injury, but its efficiency is limited by the low local concentration within the infarct. Here, we established a Tβ4 delivery system for cardiac repair based on the interaction between the abundant fibrin in the infarct zone...
Autores principales: | Huang, Zheyong, Song, Yanan, Pang, Zhiqing, Zhang, Bo, Yang, Hongbo, Shi, Hongtao, Chen, Jing, Gong, Hui, Qian, Juying, Ge, Junbo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396927/ https://www.ncbi.nlm.nih.gov/pubmed/28442910 http://dx.doi.org/10.2147/IJN.S131949 |
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