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Soluble cytotoxic T-lymphocyte antigen 4: a favorable predictor in malignant tumors after therapy

PURPOSE: Soluble cytotoxic T-lymphocyte antigen 4 (sCTLA-4), one of the isoforms of CTLA-4, was discovered to be critical in downregulating the negative signal of CTLA-4 in T-cell responses. Contrary to the classical immunosuppressive effect of CTLA-4, its immunoregulatory function might be complica...

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Detalles Bibliográficos
Autores principales:	Liu, Qiqi, Hu, Pingping, Deng, Guodong, Zhang, Jingxin, Liang, Ning, Xie, Jian, Qiao, Lili, Luo, Hui, Zhang, Jiandong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2017
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396933/ https://www.ncbi.nlm.nih.gov/pubmed/28442923 http://dx.doi.org/10.2147/OTT.S128451

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