Identification of senescence-associated circular RNAs (SAC-RNAs) reveals senescence suppressor CircPVT1

Using RNA sequencing (RNA-Seq), we compared the expression patterns of circular RNAs in proliferating (early-passage) and senescent (late-passage) human diploid WI-38 fibroblasts. Among the differentially expressed senescence-associated circRNAs (which we termed ‘SAC-RNAs’), we identified CircPVT1,...

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Detalles Bibliográficos
Autores principales: Panda, Amaresh C., Grammatikakis, Ioannis, Kim, Kyoung Mi, De, Supriyo, Martindale, Jennifer L., Munk, Rachel, Yang, Xiaoling, Abdelmohsen, Kotb, Gorospe, Myriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397146/
https://www.ncbi.nlm.nih.gov/pubmed/27928058
http://dx.doi.org/10.1093/nar/gkw1201

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