Cargando…
Handcuffing reversal is facilitated by proteases and replication initiator monomers
Specific nucleoprotein complexes are formed strictly to prevent over-initiation of DNA replication. An example of those is the so-called handcuff complex, in which two plasmid molecules are coupled together with plasmid-encoded replication initiation protein (Rep). In this work, we elucidate the mec...
Autores principales: | Bury, Katarzyna, Wegrzyn, Katarzyna, Konieczny, Igor |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397158/ https://www.ncbi.nlm.nih.gov/pubmed/28335002 http://dx.doi.org/10.1093/nar/gkx166 |
Ejemplares similares
-
Opposing effects of DNA on proteolysis of a replication initiator
por: Kubik, Slawomir, et al.
Publicado: (2012) -
Sequence-specific interactions of Rep proteins with ssDNA in the AT-rich region of the plasmid replication origin
por: Wegrzyn, Katarzyna, et al.
Publicado: (2014) -
Rep protein accommodates together dsDNA and ssDNA which enables a loop-back mechanism to plasmid DNA replication initiation
por: Wegrzyn, Katarzyna, et al.
Publicado: (2023) -
Handcuffing Peptides by a Key of Gold
por: van Maarseveen, Jan H.
Publicado: (2021) -
Defining a novel domain that provides an essential contribution to site-specific interaction of Rep protein with DNA
por: Wegrzyn, Katarzyna, et al.
Publicado: (2021)