Cargando…
KDM4B/JMJD2B is a p53 target gene that modulates the amplitude of p53 response after DNA damage
The p53 tumor suppressor protein plays a critical role in orchestrating the genomic response to various stress signals by acting as a master transcriptional regulator. Differential gene activity is controlled by transcription factors but also dependent on the underlying chromatin structure, especial...
Autores principales: | Castellini, Laura, Moon, Eui Jung, Razorenova, Olga V., Krieg, Adam J., von Eyben, Rie, Giaccia, Amato J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397198/ https://www.ncbi.nlm.nih.gov/pubmed/28073943 http://dx.doi.org/10.1093/nar/gkw1281 |
Ejemplares similares
-
Critical role for p53-serine 15 phosphorylation in stimulating transactivation at p53-responsive promoters
por: Loughery, Jayne, et al.
Publicado: (2014) -
Inhibition of p53 acetylation by INHAT subunit SET/TAF-Iβ represses p53 activity
por: Kim, Ji-Young, et al.
Publicado: (2012) -
Heme promotes transcriptional and demethylase activities of Gis1, a member of the histone demethylase JMJD2/KDM4 family
por: Lal, Sneha, et al.
Publicado: (2018) -
The complex architecture of p53 binding sites
por: Senitzki, Alon, et al.
Publicado: (2021) -
Formation of stress-specific p53 binding patterns is influenced by chromatin but not by modulation of p53 binding affinity to response elements(†)
por: Millau, Jean-François, et al.
Publicado: (2011)