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Regulation of Prp43-mediated disassembly of spliceosomes by its cofactors Ntr1 and Ntr2

The DEAH-box NTPase Prp43 disassembles spliceosomes in co-operation with the cofactors Ntr1/Spp382 and Ntr2, forming the NTR complex. How Prp43 is regulated by its cofactors to discard selectively only intron-lariat spliceosomes (ILS) and defective spliceosomes and to prevent disassembly of earlier...

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Detalles Bibliográficos
Autores principales:	Fourmann, Jean-Baptiste, Tauchert, Marcel J., Ficner, Ralf, Fabrizio, Patrizia, Lührmann, Reinhard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397206/ https://www.ncbi.nlm.nih.gov/pubmed/27923990 http://dx.doi.org/10.1093/nar/gkw1225

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