MR1 Restricted Mucosal-Associated Invariant T (MAIT) Cells Respond to Mycobacterial Vaccination and Infection in Nonhuman Primates

Studies on mucosal-associated invariant T cells (MAITs) in nonhuman primates (NHP), a physiologically relevant model of human immunity, are handicapped due to a lack of macaque MAIT-specific reagents. Here we show that while MR1 ligand-contact residues are conserved between human and multiple NHP sp...

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Detalles Bibliográficos
Autores principales: Greene, Justin M., Dash, Pradyot, Roy, Sobhan, McMurtrey, Curtis, Awad, Walid, Reed, Jason S., Hammond, Katherine B., Abdulhaqq, Shaheed, Wu, Helen L., Burwitz, Benjamin J., Roth, Benjamin F., Morrow, David W., Ford, Julia C., Xu, Guangwu, Bae, Joseph Y., Crank, Hugh, Legasse, Alfred W., Dang, Thurston H., Greenaway, Hui Yee, Kurniawan, Monica, Gold, Marielle C., Harriff, Melanie J., Lewinsohn, Deborah A., Park, Byung S., Axthelm, Michael K., Stanton, Jeffrey J., Hansen, Scott G., Picker, Louis J., Venturi, Vanessa, Hildebrand, William, Thomas, Paul G., Lewinsohn, David M., Adams, Erin J., Sacha, Jonah B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397382/
https://www.ncbi.nlm.nih.gov/pubmed/27759023
http://dx.doi.org/10.1038/mi.2016.91

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