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Lack of Effects of Metformin and AICAR Chronic Infusion on the Development of Hypertension in Dahl Salt-Sensitive Rats
In the kidney, reabsorption via the epithelial sodium channel (ENaC) is involved in long-term blood pressure control. Previously we demonstrated that ENaC hyperactivity is associated with development of salt-sensitive (SS) hypertension in Dahl SS rats. AMP-activated kinase (AMPK), playing a role in...
Autores principales: | Pavlov, Tengis S., Levchenko, Vladislav, Ilatovskaya, Daria V., Li, Hui, Palygin, Oleg, Pastor-Soler, Nuria M., Hallows, Kenneth R., Staruschenko, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397526/ https://www.ncbi.nlm.nih.gov/pubmed/28473772 http://dx.doi.org/10.3389/fphys.2017.00227 |
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