Primitive Neuro Ectodermal Tumor Arising in a Testicular Teratoma with Retroperitoneal Metastasis: A Case Report and Review of Literature

A 38-year-old man presenting with left testicular mass and extensive retroperitoneal lymphadenopathy underwent radical orchiectomy and specimen showed a germ cell tumor of primarily primitive neuroectodermal tumor mixed with mature teratoma. He then underwent RPLND, followed by adjuvant CAV (cycloph...

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Detalles Bibliográficos
Autores principales: Hu, Guodong, Wang, Andrew, Wang, Xiu, Xia, Leilei, Taylor, Benjamin L., Malkowicz, S. Buce, Lal, Priti, Maisel, Julia R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397596/
https://www.ncbi.nlm.nih.gov/pubmed/28443239
http://dx.doi.org/10.1016/j.eucr.2016.11.025
Descripción
Sumario:A 38-year-old man presenting with left testicular mass and extensive retroperitoneal lymphadenopathy underwent radical orchiectomy and specimen showed a germ cell tumor of primarily primitive neuroectodermal tumor mixed with mature teratoma. He then underwent RPLND, followed by adjuvant CAV (cyclophosphamide, doxorubicin, vincristine) and IE (ifosfamide, etoposide) alternating chemotherapy given the high rate of recurrence and high rate of response to the PNET-specific chemotherapy.

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