Cargando…

Incidental Leydig Cell Tumor in Patient with Hormone Resistant Prostate Cancer

We hereby present the case of a 55 years old patient with clinical diagnosis of high-risk prostate cancer T2bN1Mo Gleason 9 (4 + 5) treated with androgen deprivation therapy and external beam radiotherapy. Despite treatment, castration levels were not achieved and clinical progression was evidenced...

Descripción completa

Detalles Bibliográficos
Autores principales: Sánchez Pérez, M., Jiménez Marrero, P., Kim Lee, D., Neumann, M.P., Jorge Pérez, N., Hernández Hernández, C., Hernández Escobar, S., Marrero Domínguez, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397599/
https://www.ncbi.nlm.nih.gov/pubmed/28443242
http://dx.doi.org/10.1016/j.eucr.2017.03.027
_version_ 1783230293689237504
author Sánchez Pérez, M.
Jiménez Marrero, P.
Kim Lee, D.
Neumann, M.P.
Jorge Pérez, N.
Hernández Hernández, C.
Hernández Escobar, S.
Marrero Domínguez, R.
author_facet Sánchez Pérez, M.
Jiménez Marrero, P.
Kim Lee, D.
Neumann, M.P.
Jorge Pérez, N.
Hernández Hernández, C.
Hernández Escobar, S.
Marrero Domínguez, R.
author_sort Sánchez Pérez, M.
collection PubMed
description We hereby present the case of a 55 years old patient with clinical diagnosis of high-risk prostate cancer T2bN1Mo Gleason 9 (4 + 5) treated with androgen deprivation therapy and external beam radiotherapy. Despite treatment, castration levels were not achieved and clinical progression was evidenced by the appearance of bone metastases and progression of PSA. After several hormonal treatments without any PSA or testosterone response, surgical castration was performed by bilateral orchiectomy. The pathology results showed an incidental Leydig cell tumor in the right testicle.
format Online
Article
Text
id pubmed-5397599
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-53975992017-04-25 Incidental Leydig Cell Tumor in Patient with Hormone Resistant Prostate Cancer Sánchez Pérez, M. Jiménez Marrero, P. Kim Lee, D. Neumann, M.P. Jorge Pérez, N. Hernández Hernández, C. Hernández Escobar, S. Marrero Domínguez, R. Urol Case Rep Oncology We hereby present the case of a 55 years old patient with clinical diagnosis of high-risk prostate cancer T2bN1Mo Gleason 9 (4 + 5) treated with androgen deprivation therapy and external beam radiotherapy. Despite treatment, castration levels were not achieved and clinical progression was evidenced by the appearance of bone metastases and progression of PSA. After several hormonal treatments without any PSA or testosterone response, surgical castration was performed by bilateral orchiectomy. The pathology results showed an incidental Leydig cell tumor in the right testicle. Elsevier 2017-04-19 /pmc/articles/PMC5397599/ /pubmed/28443242 http://dx.doi.org/10.1016/j.eucr.2017.03.027 Text en © 2017 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Oncology
Sánchez Pérez, M.
Jiménez Marrero, P.
Kim Lee, D.
Neumann, M.P.
Jorge Pérez, N.
Hernández Hernández, C.
Hernández Escobar, S.
Marrero Domínguez, R.
Incidental Leydig Cell Tumor in Patient with Hormone Resistant Prostate Cancer
title Incidental Leydig Cell Tumor in Patient with Hormone Resistant Prostate Cancer
title_full Incidental Leydig Cell Tumor in Patient with Hormone Resistant Prostate Cancer
title_fullStr Incidental Leydig Cell Tumor in Patient with Hormone Resistant Prostate Cancer
title_full_unstemmed Incidental Leydig Cell Tumor in Patient with Hormone Resistant Prostate Cancer
title_short Incidental Leydig Cell Tumor in Patient with Hormone Resistant Prostate Cancer
title_sort incidental leydig cell tumor in patient with hormone resistant prostate cancer
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397599/
https://www.ncbi.nlm.nih.gov/pubmed/28443242
http://dx.doi.org/10.1016/j.eucr.2017.03.027
work_keys_str_mv AT sanchezperezm incidentalleydigcelltumorinpatientwithhormoneresistantprostatecancer
AT jimenezmarrerop incidentalleydigcelltumorinpatientwithhormoneresistantprostatecancer
AT kimleed incidentalleydigcelltumorinpatientwithhormoneresistantprostatecancer
AT neumannmp incidentalleydigcelltumorinpatientwithhormoneresistantprostatecancer
AT jorgeperezn incidentalleydigcelltumorinpatientwithhormoneresistantprostatecancer
AT hernandezhernandezc incidentalleydigcelltumorinpatientwithhormoneresistantprostatecancer
AT hernandezescobars incidentalleydigcelltumorinpatientwithhormoneresistantprostatecancer
AT marrerodominguezr incidentalleydigcelltumorinpatientwithhormoneresistantprostatecancer