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Incidental Leydig Cell Tumor in Patient with Hormone Resistant Prostate Cancer
We hereby present the case of a 55 years old patient with clinical diagnosis of high-risk prostate cancer T2bN1Mo Gleason 9 (4 + 5) treated with androgen deprivation therapy and external beam radiotherapy. Despite treatment, castration levels were not achieved and clinical progression was evidenced...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397599/ https://www.ncbi.nlm.nih.gov/pubmed/28443242 http://dx.doi.org/10.1016/j.eucr.2017.03.027 |
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author | Sánchez Pérez, M. Jiménez Marrero, P. Kim Lee, D. Neumann, M.P. Jorge Pérez, N. Hernández Hernández, C. Hernández Escobar, S. Marrero Domínguez, R. |
author_facet | Sánchez Pérez, M. Jiménez Marrero, P. Kim Lee, D. Neumann, M.P. Jorge Pérez, N. Hernández Hernández, C. Hernández Escobar, S. Marrero Domínguez, R. |
author_sort | Sánchez Pérez, M. |
collection | PubMed |
description | We hereby present the case of a 55 years old patient with clinical diagnosis of high-risk prostate cancer T2bN1Mo Gleason 9 (4 + 5) treated with androgen deprivation therapy and external beam radiotherapy. Despite treatment, castration levels were not achieved and clinical progression was evidenced by the appearance of bone metastases and progression of PSA. After several hormonal treatments without any PSA or testosterone response, surgical castration was performed by bilateral orchiectomy. The pathology results showed an incidental Leydig cell tumor in the right testicle. |
format | Online Article Text |
id | pubmed-5397599 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-53975992017-04-25 Incidental Leydig Cell Tumor in Patient with Hormone Resistant Prostate Cancer Sánchez Pérez, M. Jiménez Marrero, P. Kim Lee, D. Neumann, M.P. Jorge Pérez, N. Hernández Hernández, C. Hernández Escobar, S. Marrero Domínguez, R. Urol Case Rep Oncology We hereby present the case of a 55 years old patient with clinical diagnosis of high-risk prostate cancer T2bN1Mo Gleason 9 (4 + 5) treated with androgen deprivation therapy and external beam radiotherapy. Despite treatment, castration levels were not achieved and clinical progression was evidenced by the appearance of bone metastases and progression of PSA. After several hormonal treatments without any PSA or testosterone response, surgical castration was performed by bilateral orchiectomy. The pathology results showed an incidental Leydig cell tumor in the right testicle. Elsevier 2017-04-19 /pmc/articles/PMC5397599/ /pubmed/28443242 http://dx.doi.org/10.1016/j.eucr.2017.03.027 Text en © 2017 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Oncology Sánchez Pérez, M. Jiménez Marrero, P. Kim Lee, D. Neumann, M.P. Jorge Pérez, N. Hernández Hernández, C. Hernández Escobar, S. Marrero Domínguez, R. Incidental Leydig Cell Tumor in Patient with Hormone Resistant Prostate Cancer |
title | Incidental Leydig Cell Tumor in Patient with Hormone Resistant Prostate Cancer |
title_full | Incidental Leydig Cell Tumor in Patient with Hormone Resistant Prostate Cancer |
title_fullStr | Incidental Leydig Cell Tumor in Patient with Hormone Resistant Prostate Cancer |
title_full_unstemmed | Incidental Leydig Cell Tumor in Patient with Hormone Resistant Prostate Cancer |
title_short | Incidental Leydig Cell Tumor in Patient with Hormone Resistant Prostate Cancer |
title_sort | incidental leydig cell tumor in patient with hormone resistant prostate cancer |
topic | Oncology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397599/ https://www.ncbi.nlm.nih.gov/pubmed/28443242 http://dx.doi.org/10.1016/j.eucr.2017.03.027 |
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