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Advanced Age as a Predictor of Survival and Weaning in Venoarterial Extracorporeal Oxygenation: A Retrospective Observational Study

Background. In most reports on ECMO treatment, advanced age is classified as a contraindication to VA ECMO. We attempted to investigate whether advanced age would be a main risk factor deciding VA ECMO application and performing VA ECMO support. We determined whether advanced age should be regarded...

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Autores principales: Lee, WooSurng, Kim, YoHan, Choi, HyunHee, Kim, HyoungSoo, Lee, SunHee, Lee, HeeSung, Chee, HyunKeun, Kim, JunSeok, Hwang, JaeJoon, Lee, SongAm, Kim, YongHun, Cho, SeongJoon, Ryu, SeMin, Park, SungMin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397620/
https://www.ncbi.nlm.nih.gov/pubmed/28484710
http://dx.doi.org/10.1155/2017/3505784
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author Lee, WooSurng
Kim, YoHan
Choi, HyunHee
Kim, HyoungSoo
Lee, SunHee
Lee, HeeSung
Chee, HyunKeun
Kim, JunSeok
Hwang, JaeJoon
Lee, SongAm
Kim, YongHun
Cho, SeongJoon
Ryu, SeMin
Park, SungMin
author_facet Lee, WooSurng
Kim, YoHan
Choi, HyunHee
Kim, HyoungSoo
Lee, SunHee
Lee, HeeSung
Chee, HyunKeun
Kim, JunSeok
Hwang, JaeJoon
Lee, SongAm
Kim, YongHun
Cho, SeongJoon
Ryu, SeMin
Park, SungMin
author_sort Lee, WooSurng
collection PubMed
description Background. In most reports on ECMO treatment, advanced age is classified as a contraindication to VA ECMO. We attempted to investigate whether advanced age would be a main risk factor deciding VA ECMO application and performing VA ECMO support. We determined whether advanced age should be regarded as an absolute or relative contraindication to VA ECMO and could affect weaning and survival rates of VA ECMO patients. Methods. VA ECMO was performed on 135 adult patients with primary cardiogenic shock between January 2010 and December 2014. Successful weaning was defined as weaning from ECMO followed by survival for more than 48 hours. Results. Among the 135 patients, 35 survived and were discharged uneventfully, and the remaining 100 did not survive. There were significant differences in survival between age groups, and older age showed a lower survival rate with statistical significance (P = .01). By multivariate logistic regression analysis, age was not significantly associated with in-hospital mortality (P = .83) and was not significantly associated with VA ECMO weaning (P = .11). Conclusions. Advanced age is an undeniable risk factor for VA ECMO; however, patients of advanced age should not be excluded from the chance of recovery after VA ECMO treatment.
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spelling pubmed-53976202017-05-08 Advanced Age as a Predictor of Survival and Weaning in Venoarterial Extracorporeal Oxygenation: A Retrospective Observational Study Lee, WooSurng Kim, YoHan Choi, HyunHee Kim, HyoungSoo Lee, SunHee Lee, HeeSung Chee, HyunKeun Kim, JunSeok Hwang, JaeJoon Lee, SongAm Kim, YongHun Cho, SeongJoon Ryu, SeMin Park, SungMin Biomed Res Int Research Article Background. In most reports on ECMO treatment, advanced age is classified as a contraindication to VA ECMO. We attempted to investigate whether advanced age would be a main risk factor deciding VA ECMO application and performing VA ECMO support. We determined whether advanced age should be regarded as an absolute or relative contraindication to VA ECMO and could affect weaning and survival rates of VA ECMO patients. Methods. VA ECMO was performed on 135 adult patients with primary cardiogenic shock between January 2010 and December 2014. Successful weaning was defined as weaning from ECMO followed by survival for more than 48 hours. Results. Among the 135 patients, 35 survived and were discharged uneventfully, and the remaining 100 did not survive. There were significant differences in survival between age groups, and older age showed a lower survival rate with statistical significance (P = .01). By multivariate logistic regression analysis, age was not significantly associated with in-hospital mortality (P = .83) and was not significantly associated with VA ECMO weaning (P = .11). Conclusions. Advanced age is an undeniable risk factor for VA ECMO; however, patients of advanced age should not be excluded from the chance of recovery after VA ECMO treatment. Hindawi 2017 2017-04-06 /pmc/articles/PMC5397620/ /pubmed/28484710 http://dx.doi.org/10.1155/2017/3505784 Text en Copyright © 2017 WooSurng Lee et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Lee, WooSurng
Kim, YoHan
Choi, HyunHee
Kim, HyoungSoo
Lee, SunHee
Lee, HeeSung
Chee, HyunKeun
Kim, JunSeok
Hwang, JaeJoon
Lee, SongAm
Kim, YongHun
Cho, SeongJoon
Ryu, SeMin
Park, SungMin
Advanced Age as a Predictor of Survival and Weaning in Venoarterial Extracorporeal Oxygenation: A Retrospective Observational Study
title Advanced Age as a Predictor of Survival and Weaning in Venoarterial Extracorporeal Oxygenation: A Retrospective Observational Study
title_full Advanced Age as a Predictor of Survival and Weaning in Venoarterial Extracorporeal Oxygenation: A Retrospective Observational Study
title_fullStr Advanced Age as a Predictor of Survival and Weaning in Venoarterial Extracorporeal Oxygenation: A Retrospective Observational Study
title_full_unstemmed Advanced Age as a Predictor of Survival and Weaning in Venoarterial Extracorporeal Oxygenation: A Retrospective Observational Study
title_short Advanced Age as a Predictor of Survival and Weaning in Venoarterial Extracorporeal Oxygenation: A Retrospective Observational Study
title_sort advanced age as a predictor of survival and weaning in venoarterial extracorporeal oxygenation: a retrospective observational study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397620/
https://www.ncbi.nlm.nih.gov/pubmed/28484710
http://dx.doi.org/10.1155/2017/3505784
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