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Trial Sequential Analysis in systematic reviews with meta-analysis

BACKGROUND: Most meta-analyses in systematic reviews, including Cochrane ones, do not have sufficient statistical power to detect or refute even large intervention effects. This is why a meta-analysis ought to be regarded as an interim analysis on its way towards a required information size. The res...

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Detalles Bibliográficos
Autores principales:	Wetterslev, Jørn, Jakobsen, Janus Christian, Gluud, Christian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397700/ https://www.ncbi.nlm.nih.gov/pubmed/28264661 http://dx.doi.org/10.1186/s12874-017-0315-7

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