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Association between Fcγ receptor IIA, IIIA and IIIB genetic polymorphisms and susceptibility to severe malaria anemia in children in western Kenya

BACKGROUND: Naturally-acquired immunity to Plasmodium falciparum malaria develops after several episodes of infection. Fc gamma receptors (FcγRs) bind to immunoglobulin G (IgG) antibodies and mediate phagocytosis of opsonized microbes, thereby, linking humoral and cellular immunity. FcγR polymorphis...

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Detalles Bibliográficos
Autores principales: Munde, Elly O., Okeyo, Winnie A., Raballah, Evans, Anyona, Samuel B., Were, Tom, Ong’echa, John M., Perkins, Douglas J., Ouma, Collins
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397742/
https://www.ncbi.nlm.nih.gov/pubmed/28427365
http://dx.doi.org/10.1186/s12879-017-2390-0