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IFNβ Protects Neurons from Damage in a Murine Model of HIV-1 Associated Brain Injury

Infection with human immunodeficiency virus-1 (HIV-1) causes brain injury. Type I interferons (IFNα/β) are critical mediators of any anti-viral immune response and IFNβ has been implicated in the temporary control of lentiviral infection in the brain. Here we show that transgenic mice expressing HIV...

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Detalles Bibliográficos
Autores principales: Thaney, Victoria E., O’Neill, Alan M., Hoefer, Melanie M., Maung, Ricky, Sanchez, Ana B., Kaul, Marcus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397848/
https://www.ncbi.nlm.nih.gov/pubmed/28425451
http://dx.doi.org/10.1038/srep46514