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IFNβ Protects Neurons from Damage in a Murine Model of HIV-1 Associated Brain Injury
Infection with human immunodeficiency virus-1 (HIV-1) causes brain injury. Type I interferons (IFNα/β) are critical mediators of any anti-viral immune response and IFNβ has been implicated in the temporary control of lentiviral infection in the brain. Here we show that transgenic mice expressing HIV...
Autores principales: | Thaney, Victoria E., O’Neill, Alan M., Hoefer, Melanie M., Maung, Ricky, Sanchez, Ana B., Kaul, Marcus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397848/ https://www.ncbi.nlm.nih.gov/pubmed/28425451 http://dx.doi.org/10.1038/srep46514 |
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