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Role of Drug Metabolism in the Cytotoxicity and Clinical Efficacy of Anthracyclines
Many clinical studies involving anti-tumor agents neglect to consider how these agents are metabolized within the host and whether the creation of specific metabolites alters drug therapeutic properties or toxic side effects. However, this is not the case for the anthracycline class of chemotherapy...
Autores principales: | Edwardson, Derek W., Narendrula, Rashmi, Chewchuk, Simon, Mispel-Beyer, Kyle, Mapletoft, Jonathan P.J., Parissenti, Amadeo M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bentham Science Publishers
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398089/ https://www.ncbi.nlm.nih.gov/pubmed/26321196 http://dx.doi.org/10.2174/1389200216888150915112039 |
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