Biofilm and the Role of Antibiotics in the Treatment of Periprosthetic Hip and Knee Joint Infections

An increasing demand for lower limb arthroplasty will lead to a proportionate increase in the need for revision surgery. A notable proportion of revision surgery is secondary to periprosthetic joint infections (PJI). Diagnosing and eradicating PJI can form a very difficult challenge. An important ca...

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Autores principales: Mirza, Yusuf H., Tansey, Rosamond, Sukeik, Mohamed, Shaath, Mohammed, Haddad, Fares Sami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Open 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398090/
https://www.ncbi.nlm.nih.gov/pubmed/28484579
http://dx.doi.org/10.2174/1874325001610010636
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author Mirza, Yusuf H.
Tansey, Rosamond
Sukeik, Mohamed
Shaath, Mohammed
Haddad, Fares Sami
author_facet Mirza, Yusuf H.
Tansey, Rosamond
Sukeik, Mohamed
Shaath, Mohammed
Haddad, Fares Sami
author_sort Mirza, Yusuf H.
collection PubMed
description An increasing demand for lower limb arthroplasty will lead to a proportionate increase in the need for revision surgery. A notable proportion of revision surgery is secondary to periprosthetic joint infections (PJI). Diagnosing and eradicating PJI can form a very difficult challenge. An important cause of PJI is the formation of a bacterial biofilm on the implant surface. Our review article seeks to describe biofilms; their definitions and formation, common causative bacteria, prophylactic and therapeutic antibiotic therapy.
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spelling pubmed-53980902017-05-08 Biofilm and the Role of Antibiotics in the Treatment of Periprosthetic Hip and Knee Joint Infections Mirza, Yusuf H. Tansey, Rosamond Sukeik, Mohamed Shaath, Mohammed Haddad, Fares Sami Open Orthop J Article An increasing demand for lower limb arthroplasty will lead to a proportionate increase in the need for revision surgery. A notable proportion of revision surgery is secondary to periprosthetic joint infections (PJI). Diagnosing and eradicating PJI can form a very difficult challenge. An important cause of PJI is the formation of a bacterial biofilm on the implant surface. Our review article seeks to describe biofilms; their definitions and formation, common causative bacteria, prophylactic and therapeutic antibiotic therapy. Bentham Open 2016-11-30 /pmc/articles/PMC5398090/ /pubmed/28484579 http://dx.doi.org/10.2174/1874325001610010636 Text en © Mirza et al.; Licensee Bentham Open https://creativecommons.org/licenses/by/4.0/legalcode This is an open access article licensed under the terms of the Creative Commons Attribution-Non-Commercial 4.0 International Public License (CC BY-NC 4.0) (https://creativecommons.org/licenses/by-nc/4.0/legalcode), which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
spellingShingle Article
Mirza, Yusuf H.
Tansey, Rosamond
Sukeik, Mohamed
Shaath, Mohammed
Haddad, Fares Sami
Biofilm and the Role of Antibiotics in the Treatment of Periprosthetic Hip and Knee Joint Infections
title Biofilm and the Role of Antibiotics in the Treatment of Periprosthetic Hip and Knee Joint Infections
title_full Biofilm and the Role of Antibiotics in the Treatment of Periprosthetic Hip and Knee Joint Infections
title_fullStr Biofilm and the Role of Antibiotics in the Treatment of Periprosthetic Hip and Knee Joint Infections
title_full_unstemmed Biofilm and the Role of Antibiotics in the Treatment of Periprosthetic Hip and Knee Joint Infections
title_short Biofilm and the Role of Antibiotics in the Treatment of Periprosthetic Hip and Knee Joint Infections
title_sort biofilm and the role of antibiotics in the treatment of periprosthetic hip and knee joint infections
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398090/
https://www.ncbi.nlm.nih.gov/pubmed/28484579
http://dx.doi.org/10.2174/1874325001610010636
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