Spatiotemporal Changes in P-glycoprotein Levels in Brain and Peripheral Tissues Following Ischemic Stroke in Rats

P-glycoprotein (P-gp) is known to transport a diverse array of xenobiotics, including therapeutic drugs. A member of the ATP-binding cassette (ABC) transporter family, P-gp is a protein encoded by the gene Mdr1 in humans and Abcb1 in rodents (represented by 2 isoforms Abcb1a and Abcb1b). Lining the...

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Detalles Bibliográficos
Autores principales: DeMars, Kelly M, Yang, Changjun, Hawkins, Kimberly E, McCrea, Austin O, Siwarski, David M, Candelario-Jalil, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398227/
https://www.ncbi.nlm.nih.gov/pubmed/28469478
http://dx.doi.org/10.1177/1179069517701741

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398227/
https://www.ncbi.nlm.nih.gov/pubmed/28469478
http://dx.doi.org/10.1177/1179069517701741

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