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Role of H-FABP values in determining the etiologic factors of the cardiac injuries
INTRODUCTION: Cardiac injury resulting from blunt thoracic trauma is a frequent clinical occurrence which is difficult to diagnose. Our purpose in this study was to research whether H-FABP, which is a new marker for the diagnosis of cardiac injury, can be used in this patient group. METHODS: 50 pati...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The African Field Epidemiology Network
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398237/ https://www.ncbi.nlm.nih.gov/pubmed/28451014 http://dx.doi.org/10.11604/pamj.2017.26.36.8746 |
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author | Akpinar, Guleser Duman, Ali Gulen, Bedia Kapci, Mucahit Altinbilek, Ertugrul Ikizceli, Ibrahim |
author_facet | Akpinar, Guleser Duman, Ali Gulen, Bedia Kapci, Mucahit Altinbilek, Ertugrul Ikizceli, Ibrahim |
author_sort | Akpinar, Guleser |
collection | PubMed |
description | INTRODUCTION: Cardiac injury resulting from blunt thoracic trauma is a frequent clinical occurrence which is difficult to diagnose. Our purpose in this study was to research whether H-FABP, which is a new marker for the diagnosis of cardiac injury, can be used in this patient group. METHODS: 50 patients with blunt thoracic injury who were admitted to our emergency service within a period of 8 months and 50 cases as controls were included in our study. RESULTS: Of the 50 patients with blunt thoracic injury in our study, 88% were male while 12% were female. The average age of the patients was 43 ± 15.15. While 27 (54%) of the 50 patients with blunt thoracic injury had cardiac injury, 23 (46%) did not have cardiac injury. The results of the statistical analyses showed a significant association between thorax trauma and cTnI, CPK, CPKMB and H-FABP (p<0.05). While there was a significant association between cardiac injury resulting from thoracic trauma and cTnI, ECG and TTE (p<0.05), there was no significant association between CPK, CPKMB and H-FABP (p>0.05). CONCLUSION: In thoracic traumas, cardiac injury diagnosis can be made as a result of the assessment with Troponin-I, ECG and ECHO. For cardiac injury diagnosis, wide scale prospective studies are needed for H-FABP use. |
format | Online Article Text |
id | pubmed-5398237 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | The African Field Epidemiology Network |
record_format | MEDLINE/PubMed |
spelling | pubmed-53982372017-04-27 Role of H-FABP values in determining the etiologic factors of the cardiac injuries Akpinar, Guleser Duman, Ali Gulen, Bedia Kapci, Mucahit Altinbilek, Ertugrul Ikizceli, Ibrahim Pan Afr Med J Research INTRODUCTION: Cardiac injury resulting from blunt thoracic trauma is a frequent clinical occurrence which is difficult to diagnose. Our purpose in this study was to research whether H-FABP, which is a new marker for the diagnosis of cardiac injury, can be used in this patient group. METHODS: 50 patients with blunt thoracic injury who were admitted to our emergency service within a period of 8 months and 50 cases as controls were included in our study. RESULTS: Of the 50 patients with blunt thoracic injury in our study, 88% were male while 12% were female. The average age of the patients was 43 ± 15.15. While 27 (54%) of the 50 patients with blunt thoracic injury had cardiac injury, 23 (46%) did not have cardiac injury. The results of the statistical analyses showed a significant association between thorax trauma and cTnI, CPK, CPKMB and H-FABP (p<0.05). While there was a significant association between cardiac injury resulting from thoracic trauma and cTnI, ECG and TTE (p<0.05), there was no significant association between CPK, CPKMB and H-FABP (p>0.05). CONCLUSION: In thoracic traumas, cardiac injury diagnosis can be made as a result of the assessment with Troponin-I, ECG and ECHO. For cardiac injury diagnosis, wide scale prospective studies are needed for H-FABP use. The African Field Epidemiology Network 2017-01-24 /pmc/articles/PMC5398237/ /pubmed/28451014 http://dx.doi.org/10.11604/pamj.2017.26.36.8746 Text en © Guleser Akpinar et al. http://creativecommons.org/licenses/by/2.0/ The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Akpinar, Guleser Duman, Ali Gulen, Bedia Kapci, Mucahit Altinbilek, Ertugrul Ikizceli, Ibrahim Role of H-FABP values in determining the etiologic factors of the cardiac injuries |
title | Role of H-FABP values in determining the etiologic factors of the cardiac injuries |
title_full | Role of H-FABP values in determining the etiologic factors of the cardiac injuries |
title_fullStr | Role of H-FABP values in determining the etiologic factors of the cardiac injuries |
title_full_unstemmed | Role of H-FABP values in determining the etiologic factors of the cardiac injuries |
title_short | Role of H-FABP values in determining the etiologic factors of the cardiac injuries |
title_sort | role of h-fabp values in determining the etiologic factors of the cardiac injuries |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398237/ https://www.ncbi.nlm.nih.gov/pubmed/28451014 http://dx.doi.org/10.11604/pamj.2017.26.36.8746 |
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