Cargando…

Role of H-FABP values in determining the etiologic factors of the cardiac injuries

INTRODUCTION: Cardiac injury resulting from blunt thoracic trauma is a frequent clinical occurrence which is difficult to diagnose. Our purpose in this study was to research whether H-FABP, which is a new marker for the diagnosis of cardiac injury, can be used in this patient group. METHODS: 50 pati...

Descripción completa

Detalles Bibliográficos
Autores principales: Akpinar, Guleser, Duman, Ali, Gulen, Bedia, Kapci, Mucahit, Altinbilek, Ertugrul, Ikizceli, Ibrahim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398237/
https://www.ncbi.nlm.nih.gov/pubmed/28451014
http://dx.doi.org/10.11604/pamj.2017.26.36.8746
_version_ 1783230423544889344
author Akpinar, Guleser
Duman, Ali
Gulen, Bedia
Kapci, Mucahit
Altinbilek, Ertugrul
Ikizceli, Ibrahim
author_facet Akpinar, Guleser
Duman, Ali
Gulen, Bedia
Kapci, Mucahit
Altinbilek, Ertugrul
Ikizceli, Ibrahim
author_sort Akpinar, Guleser
collection PubMed
description INTRODUCTION: Cardiac injury resulting from blunt thoracic trauma is a frequent clinical occurrence which is difficult to diagnose. Our purpose in this study was to research whether H-FABP, which is a new marker for the diagnosis of cardiac injury, can be used in this patient group. METHODS: 50 patients with blunt thoracic injury who were admitted to our emergency service within a period of 8 months and 50 cases as controls were included in our study. RESULTS: Of the 50 patients with blunt thoracic injury in our study, 88% were male while 12% were female. The average age of the patients was 43 ± 15.15. While 27 (54%) of the 50 patients with blunt thoracic injury had cardiac injury, 23 (46%) did not have cardiac injury. The results of the statistical analyses showed a significant association between thorax trauma and cTnI, CPK, CPKMB and H-FABP (p<0.05). While there was a significant association between cardiac injury resulting from thoracic trauma and cTnI, ECG and TTE (p<0.05), there was no significant association between CPK, CPKMB and H-FABP (p>0.05). CONCLUSION: In thoracic traumas, cardiac injury diagnosis can be made as a result of the assessment with Troponin-I, ECG and ECHO. For cardiac injury diagnosis, wide scale prospective studies are needed for H-FABP use.
format Online
Article
Text
id pubmed-5398237
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher The African Field Epidemiology Network
record_format MEDLINE/PubMed
spelling pubmed-53982372017-04-27 Role of H-FABP values in determining the etiologic factors of the cardiac injuries Akpinar, Guleser Duman, Ali Gulen, Bedia Kapci, Mucahit Altinbilek, Ertugrul Ikizceli, Ibrahim Pan Afr Med J Research INTRODUCTION: Cardiac injury resulting from blunt thoracic trauma is a frequent clinical occurrence which is difficult to diagnose. Our purpose in this study was to research whether H-FABP, which is a new marker for the diagnosis of cardiac injury, can be used in this patient group. METHODS: 50 patients with blunt thoracic injury who were admitted to our emergency service within a period of 8 months and 50 cases as controls were included in our study. RESULTS: Of the 50 patients with blunt thoracic injury in our study, 88% were male while 12% were female. The average age of the patients was 43 ± 15.15. While 27 (54%) of the 50 patients with blunt thoracic injury had cardiac injury, 23 (46%) did not have cardiac injury. The results of the statistical analyses showed a significant association between thorax trauma and cTnI, CPK, CPKMB and H-FABP (p<0.05). While there was a significant association between cardiac injury resulting from thoracic trauma and cTnI, ECG and TTE (p<0.05), there was no significant association between CPK, CPKMB and H-FABP (p>0.05). CONCLUSION: In thoracic traumas, cardiac injury diagnosis can be made as a result of the assessment with Troponin-I, ECG and ECHO. For cardiac injury diagnosis, wide scale prospective studies are needed for H-FABP use. The African Field Epidemiology Network 2017-01-24 /pmc/articles/PMC5398237/ /pubmed/28451014 http://dx.doi.org/10.11604/pamj.2017.26.36.8746 Text en © Guleser Akpinar et al. http://creativecommons.org/licenses/by/2.0/ The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Akpinar, Guleser
Duman, Ali
Gulen, Bedia
Kapci, Mucahit
Altinbilek, Ertugrul
Ikizceli, Ibrahim
Role of H-FABP values in determining the etiologic factors of the cardiac injuries
title Role of H-FABP values in determining the etiologic factors of the cardiac injuries
title_full Role of H-FABP values in determining the etiologic factors of the cardiac injuries
title_fullStr Role of H-FABP values in determining the etiologic factors of the cardiac injuries
title_full_unstemmed Role of H-FABP values in determining the etiologic factors of the cardiac injuries
title_short Role of H-FABP values in determining the etiologic factors of the cardiac injuries
title_sort role of h-fabp values in determining the etiologic factors of the cardiac injuries
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398237/
https://www.ncbi.nlm.nih.gov/pubmed/28451014
http://dx.doi.org/10.11604/pamj.2017.26.36.8746
work_keys_str_mv AT akpinarguleser roleofhfabpvaluesindeterminingtheetiologicfactorsofthecardiacinjuries
AT dumanali roleofhfabpvaluesindeterminingtheetiologicfactorsofthecardiacinjuries
AT gulenbedia roleofhfabpvaluesindeterminingtheetiologicfactorsofthecardiacinjuries
AT kapcimucahit roleofhfabpvaluesindeterminingtheetiologicfactorsofthecardiacinjuries
AT altinbilekertugrul roleofhfabpvaluesindeterminingtheetiologicfactorsofthecardiacinjuries
AT ikizceliibrahim roleofhfabpvaluesindeterminingtheetiologicfactorsofthecardiacinjuries