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Kynurenine Pathway of Tryptophan Metabolism: Regulatory and Functional Aspects
Regulatory and functional aspects of the kynurenine (K) pathway (KP) of tryptophan (Trp) degradation are reviewed. The KP accounts for ~95% of dietary Trp degradation, of which 90% is attributed to the hepatic KP. During immune activation, the minor extrahepatic KP plays a more active role. The KP i...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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SAGE Publications
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398323/ https://www.ncbi.nlm.nih.gov/pubmed/28469468 http://dx.doi.org/10.1177/1178646917691938 |