Cargando…

miR-4417 Targets Tripartite Motif-Containing 35 (TRIM35) and Regulates Pyruvate Kinase Muscle 2 (PKM2) Phosphorylation to Promote Proliferation and Suppress Apoptosis in Hepatocellular Carcinoma Cells

BACKGROUND: MicroRNAs (miRNAs) are a class of small non-coding RNAs that are strongly involved in various types of carcinogenesis, including hepatocellular carcinoma (HCC). This study aimed to clarify whether miR-4417 promotes HCC growth by targeting TRIM35 and regulating PKM2 phosphorylation. MATER...

Descripción completa

Detalles Bibliográficos
Autores principales:	Song, Lijie, Zhang, Weijie, Chang, Zhiwei, Pan, Yanfeng, Zong, Hong, Fan, Qingxia, Wang, Liuxing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2017
Materias:	Lab/In Vitro Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398329/ https://www.ncbi.nlm.nih.gov/pubmed/28394882 http://dx.doi.org/10.12659/MSM.900296

Ejemplares similares

Overexpression of Tripartite Motif Conaining 55 (TRIM55) Inhibits Migration and Invasion of Hepatocellular Carcinoma (HCC) Cells via Epithelial-Mesenchymal Transition and Matrix Metalloproteinase-2 (MMP2)
por: Li, Xinyu, et al.
Publicado: (2019)

Tripartite Motif Containing 52 (TRIM52) Promotes Cell Proliferation in Hepatitis B Virus-Associated Hepatocellular Carcinoma
por: Zhang, Yi, et al.
Publicado: (2017)

Expression of Tripartite Motif-Containing Proteactiin 11 (TRIM11) is Associated with the Progression of Human Prostate Cancer and is Downregulated by MicroRNA-5193
por: Pan, Yue, et al.
Publicado: (2019)

Tripartite Motif-Containing Protein 59 (TRIM59) Promotes Epithelial Ovarian Cancer Progression via the Focal Adhesion Kinase(FAK)/AKT/Matrix Metalloproteinase (MMP) Pathway
por: Zhang, Pei, et al.
Publicado: (2019)

Overexpression of Pyruvate Kinase Type M2 (PKM2) Promotes Ovarian Cancer Cell Growth and Survival Via Regulation of Cell Cycle Progression Related with Upregulated CCND1 and Downregulated CDKN1A Expression
por: Zheng, Bin, et al.
Publicado: (2018)

Mammalian Target of Rapamycin (mTOR) Regulates Transforming Growth Factor-β(1) (TGF-β(1))-Induced Epithelial-Mesenchymal Transition via Decreased Pyruvate Kinase M2 (PKM2) Expression in Cervical Cancer Cells
por: Cheng, Ke-yan, et al.
Publicado: (2017)

Tripartite Motif Containing 52 Positively Regulates NF-κB Signaling by Promoting IκBα Ubiquitination in Lipopolysaccharide-Treated Microglial Cell Activation
por: Zhang, Pei, et al.
Publicado: (2020)

3,5-Dicaffeoylquinic Acid Disperses Aspergillus Fumigatus Biofilm and Enhances Fungicidal Efficacy of Voriconazole and Amphotericin B
por: Luo, Jing, et al.
Publicado: (2018)

Co-expression of PKM2 and TRIM35 predicts survival and recurrence in hepatocellular carcinoma
por: Chen, Zhiao, et al.
Publicado: (2014)

Downregulation of miR-33 Has Protective Effect Against Aβ(25–35)-Induced Injury in SH-SH-SY5Y Cells
por: Wang, Xiaoping, et al.
Publicado: (2020)

Curcumin Treatment is Associated with Increased Expression of the N-Methyl-D-Aspartate Receptor (NMDAR) Subunit, NR2A, in a Rat PC12 Cell Line Model of Alzheimer’s Disease Treated with the Acetyl Amyloid-β Peptide, Aβ(25–35)
por: Qian, Wei, et al.
Publicado: (2018)

Chemokine (C-C Motif) Ligand 2/Chemokine Receptor 2 (CCR2) Axis Blockade to Delay Chondrocyte Hypertrophy as a Therapeutic Strategy for Osteoarthritis
por: Wang, Zidong, et al.
Publicado: (2021)

Circular RNA circ_C16orf62 Suppresses Cell Growth in Gastric Cancer by miR-421/Tubulin beta-2A Chain (TUBB2A) Axis
por: Jin, Yanfeng, et al.
Publicado: (2020)

Downregulated miR-524-5p Participates in the Tumor Microenvironment of Ameloblastoma by Targeting the Interleukin-33 (IL-33)/Suppression of Tumorigenicity 2 (ST2) Axis
por: Chen, Lijie, et al.
Publicado: (2020)

Ca(2+)/Calmodulin-Dependent Protein Kinase II (CaMKII) Increases Small-Conductance Ca(2+)-Activated K(+) Current in Patients with Chronic Atrial Fibrillation
por: Fan, Xuehui, et al.
Publicado: (2018)

miR-143 Induces the Apoptosis of Prostate Cancer LNCap Cells by Suppressing Bcl-2 Expression
por: Ma, Zhiwei, et al.
Publicado: (2017)

RNA-Binding Motif 4 (RBM4) Suppresses Tumor Growth and Metastasis in Human Gastric Cancer
por: Yong, Hongmei, et al.
Publicado: (2019)

A Regulatory Axis of circ_0008193/miR-1180-3p/TRIM62 Suppresses Proliferation, Migration, Invasion, and Warburg Effect in Lung Adenocarcinoma Cells Under Hypoxia
por: Chen, Minbiao, et al.
Publicado: (2020)

High RNA-Binding Motif Protein 3 (RBM3) Expression is Independently Associated with Prolonged Overall Survival in Intestinal-Type Gastric Cancer
por: Ye, Fangpeng, et al.
Publicado: (2017)

TRIM35 ubiquitination regulates the expression of PKM2 tetramer and dimer and affects the malignant behaviour of breast cancer by regulating the Warburg effect
por: Wu, Hao, et al.
Publicado: (2022)

MicroRNA-181a Regulates Apoptosis and Autophagy Process in Parkinson’s Disease by Inhibiting p38 Mitogen-Activated Protein Kinase (MAPK)/c-Jun N-Terminal Kinases (JNK) Signaling Pathways
por: Liu, Ying, et al.
Publicado: (2017)

Roles of CYP2C19 Gene Polymorphisms in Susceptibility to POAG and Individual Differences in Drug Treatment Response
por: Liu, Xiang-Long, et al.
Publicado: (2016)

Tripartite motif containing 35 contributes to the proliferation, migration, and invasion of lung cancer cells in vitro and in vivo
por: Zhang, Jingtao, et al.
Publicado: (2020)

Identification of Differentially Expressed Genes in Pelvic Organ Prolapse by RNA-Seq
por: Xie, Ruoyun, et al.
Publicado: (2016)

The Emerging Roles of Tripartite Motif Proteins (TRIMs) in Acute Lung Injury
por: Huang, Yingjie, et al.
Publicado: (2021)

Relationship Between ADAMTS8, ADAMTS18, and ADAMTS20 (A Disintegrin and Metalloproteinase with Thrombospondin Motifs) Expressions and Tumor Molecular Classification, Clinical Pathological Parameters, and Prognosis in Breast Invasive Ductal Carcinoma
por: Guo, Xuhui, et al.
Publicado: (2018)

Anticancer Effect of Radix Astragali on Cholangiocarcinoma In Vitro and Its Mechanism via Network Pharmacology
por: Wang, Yixiu, et al.
Publicado: (2020)

Role of Hydroxysteroid Dehydrogenase-Like 2 (HSDL2) in Human Ovarian Cancer
por: Sun, Qing, et al.
Publicado: (2018)

Interleukin (IL)-13, Prostaglandin E2 (PGE2), and Prostacyclin 2 (PGI2) Activate Hepatic Stellate Cells via Protein kinase C (PKC) Pathway in Hepatic Fibrosis
por: Sui, Guode, et al.
Publicado: (2018)

Nkx2–5 Regulates the Proliferation and Migration of H9c2 Cells
por: Wang, Hongshu, et al.
Publicado: (2020)

CircKIAA0907 Retards Cell Growth, Cell Cycle, and Autophagy of Gastric Cancer In Vitro and Inhibits Tumorigenesis In Vivo via the miR-452-5p/KAT6B Axis
por: Zhu, Lingyu, et al.
Publicado: (2020)

Lon Peptidase 2, Peroxisomal (LONP2) Contributes to Cervical Carcinogenesis via Oxidative Stress
por: Wu, Wangrong, et al.
Publicado: (2018)

Prognostic Significance of TNFR-Associated Factor 1 and 2 (TRAF1 and TRAF2) in Glioblastoma
por: Zhang, Wenqing, et al.
Publicado: (2017)

Sulforaphane Attenuates H(2)O(2)-induced Oxidant Stress in Human Trabecular Meshwork Cells (HTMCs) via the Phosphatidylinositol 3-Kinase (PI3K)/Serine/Threonine Kinase (Akt)-Mediated Factor-E2-Related Factor 2 (Nrf2) Signaling Activation
por: Liu, Yuzhen, et al.
Publicado: (2019)

Regulation of innate immune signalling pathways by the tripartite motif (TRIM) family proteins
por: Kawai, Taro, et al.
Publicado: (2011)

Cryptochrome 2 (CRY2) Suppresses Proliferation and Migration and Regulates Clock Gene Network in Osteosarcoma Cells
por: Yu, Yueming, et al.
Publicado: (2018)

Effects of Enhancer of Zeste Homolog 2 (EZH2) Expression on Brain Glioma Cell Proliferation and Tumorigenesis
por: Cheng, Tianci, et al.
Publicado: (2018)

P53 and Protein Phosphorylation Regulate the Oncogenic Role of Epithelial Cell Transforming 2 (ECT2)
por: Chen, Yan, et al.
Publicado: (2017)

Plasma Levels of Cyclooxygenase-2 (COX-2) and Visfatin During Different Stages and Different Subtypes of Migraine Headaches
por: Li, Chao, et al.
Publicado: (2017)

Knockdown of Ubiquitin Associated Protein 2-Like (UBAP2L) Inhibits Growth and Metastasis of Hepatocellular Carcinoma
por: Li, Qian, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_rbu31ue2ncna0c0nnilo1kqqgd