Human African trypanosomiasis control: Achievements and challenges

Sleeping sickness, also known as human African trypanosomiasis (HAT), is a neglected disease that impacts 70 million people living in 1.55 million km(2) in sub-Saharan Africa. Since the beginning of the 20th century, there have been multiple HAT epidemics in sub-Saharan Africa, with the most recent...

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Detalles Bibliográficos
Autores principales: Aksoy, Serap, Buscher, Phillipe, Lehane, Mike, Solano, Philippe, Van Den Abbeele, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Viewpoints
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398477/
https://www.ncbi.nlm.nih.gov/pubmed/28426685
http://dx.doi.org/10.1371/journal.pntd.0005454
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author Aksoy, Serap
Buscher, Phillipe
Lehane, Mike
Solano, Philippe
Van Den Abbeele, Jan
author_facet Aksoy, Serap
Buscher, Phillipe
Lehane, Mike
Solano, Philippe
Van Den Abbeele, Jan
author_sort Aksoy, Serap
collection PubMed
description Sleeping sickness, also known as human African trypanosomiasis (HAT), is a neglected disease that impacts 70 million people living in 1.55 million km(2) in sub-Saharan Africa. Since the beginning of the 20th century, there have been multiple HAT epidemics in sub-Saharan Africa, with the most recent epidemic in the 1990s resulting in about half a million HAT cases reported between 1990 and 2015. Here we review the status of HAT disease at the current time and the toolbox available for its control. We also highlight future opportunities under development towards novel or improved interventions.
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spelling pubmed-53984772017-05-04 Human African trypanosomiasis control: Achievements and challenges Aksoy, Serap Buscher, Phillipe Lehane, Mike Solano, Philippe Van Den Abbeele, Jan PLoS Negl Trop Dis Viewpoints Sleeping sickness, also known as human African trypanosomiasis (HAT), is a neglected disease that impacts 70 million people living in 1.55 million km(2) in sub-Saharan Africa. Since the beginning of the 20th century, there have been multiple HAT epidemics in sub-Saharan Africa, with the most recent epidemic in the 1990s resulting in about half a million HAT cases reported between 1990 and 2015. Here we review the status of HAT disease at the current time and the toolbox available for its control. We also highlight future opportunities under development towards novel or improved interventions. Public Library of Science 2017-04-20 /pmc/articles/PMC5398477/ /pubmed/28426685 http://dx.doi.org/10.1371/journal.pntd.0005454 Text en © 2017 Aksoy et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Viewpoints
Aksoy, Serap
Buscher, Phillipe
Lehane, Mike
Solano, Philippe
Van Den Abbeele, Jan
Human African trypanosomiasis control: Achievements and challenges
title Human African trypanosomiasis control: Achievements and challenges
title_full Human African trypanosomiasis control: Achievements and challenges
title_fullStr Human African trypanosomiasis control: Achievements and challenges
title_full_unstemmed Human African trypanosomiasis control: Achievements and challenges
title_short Human African trypanosomiasis control: Achievements and challenges
title_sort human african trypanosomiasis control: achievements and challenges
topic Viewpoints
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398477/
https://www.ncbi.nlm.nih.gov/pubmed/28426685
http://dx.doi.org/10.1371/journal.pntd.0005454
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