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Joint genetic analysis using variant sets reveals polygenic gene-context interactions

Joint genetic models for multiple traits have helped to enhance association analyses. Most existing multi-trait models have been designed to increase power for detecting associations, whereas the analysis of interactions has received considerably less attention. Here, we propose iSet, a method based...

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Detalles Bibliográficos
Autores principales: Casale, Francesco Paolo, Horta, Danilo, Rakitsch, Barbara, Stegle, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398484/
https://www.ncbi.nlm.nih.gov/pubmed/28426829
http://dx.doi.org/10.1371/journal.pgen.1006693

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