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Joint genetic analysis using variant sets reveals polygenic gene-context interactions
Joint genetic models for multiple traits have helped to enhance association analyses. Most existing multi-trait models have been designed to increase power for detecting associations, whereas the analysis of interactions has received considerably less attention. Here, we propose iSet, a method based...
Autores principales: | Casale, Francesco Paolo, Horta, Danilo, Rakitsch, Barbara, Stegle, Oliver |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398484/ https://www.ncbi.nlm.nih.gov/pubmed/28426829 http://dx.doi.org/10.1371/journal.pgen.1006693 |
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