Effect of mitochondrially targeted carboxy proxyl nitroxide on Akt-mediated survival in Daudi cells: Significance of a dual mode of action

Vicious cycles of mutations and reactive oxygen species (ROS) generation contribute to cancer progression. The use of antioxidants to inhibit ROS generation promotes cytostasis by affecting the mutation cycle and ROS-dependent survival signaling. However, cancer cells select mutations to elevate ROS...

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Detalles Bibliográficos
Autores principales: Variar, Gokul, Pant, Tarun, Singh, Apoorva, Ravichandran, Abinaya, Swami, Sushant, Kalyanaraman, Balaraman, Dhanasekaran, Anuradha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398517/
https://www.ncbi.nlm.nih.gov/pubmed/28426671
http://dx.doi.org/10.1371/journal.pone.0174546

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398517/
https://www.ncbi.nlm.nih.gov/pubmed/28426671
http://dx.doi.org/10.1371/journal.pone.0174546

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