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Reactive oxygen species are required for driving efficient and sustained aerobic glycolysis during CD4(+) T cell activation
The immune system is necessary for protecting against various pathogens. However, under certain circumstances, self-reactive immune cells can drive autoimmunity, like that exhibited in type 1 diabetes (T1D). CD4(+) T cells are major contributors to the immunopathology in T1D, and in order to drive o...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398529/ https://www.ncbi.nlm.nih.gov/pubmed/28426686 http://dx.doi.org/10.1371/journal.pone.0175549 |