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Functional genetic variant of WW domain-containing oxidoreductase (WWOX) gene is associated with hepatocellular carcinoma risk

BACKGROUND: Hepatocellular carcinoma (HCC) is one of the most common malignant tumors worldwide. Human WW domain-containing oxidoreductase (WWOX) gene has been identified as a tumor suppressor gene in multiple cancers. We hypothesize that genetic variations in WWOX are associated with HCC risk. METH...

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Detalles Bibliográficos
Autores principales: Lee, Hsiang-Lin, Cheng, Hsin-Lin, Liu, Yu-Fan, Chou, Ming-Chih, Yang, Shun-Fa, Chou, Ying-Erh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398630/
https://www.ncbi.nlm.nih.gov/pubmed/28426730
http://dx.doi.org/10.1371/journal.pone.0176141