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Medical Versus Interventional Treatment of Intra-Abdominal Abscess in Patients With Crohn Disease

BACKGROUND: Few studies exist to guide the treatment approach to intra-abdominal abscesses in Crohn disease, which can include antimicrobials alone or in conjunction with percutaneous drainage or surgery. The primary aim of this study is to review outcomes from different treatment approaches to intr...

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Autores principales: Graham, Emily, Rao, Krishna, Cinti, Sandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398645/
https://www.ncbi.nlm.nih.gov/pubmed/28469460
http://dx.doi.org/10.1177/1179916117701736
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author Graham, Emily
Rao, Krishna
Cinti, Sandro
author_facet Graham, Emily
Rao, Krishna
Cinti, Sandro
author_sort Graham, Emily
collection PubMed
description BACKGROUND: Few studies exist to guide the treatment approach to intra-abdominal abscesses in Crohn disease, which can include antimicrobials alone or in conjunction with percutaneous drainage or surgery. The primary aim of this study is to review outcomes from different treatment approaches to intra-abdominal abscess in Crohn disease. METHODS: Medical records were reviewed for patients admitted to the University of Michigan health care system with Crohn disease and intra-abdominal abscess over a 4-year period. Outcomes were compared among medical and interventional approaches. The χ(2) test was used to test for statistical significance. RESULTS: Of the 33 patients included, 13 were in the medical group and 20 were in the interventional group. Abscess recurrence/nonresolution occurred in 31% of patients in the medical group and 25% of patients in the interventional group (P = .7). CONCLUSIONS: In this study, there was no significant difference in outcome between medical and interventional therapy for intra-abdominal abscess in Crohn disease.
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spelling pubmed-53986452017-05-03 Medical Versus Interventional Treatment of Intra-Abdominal Abscess in Patients With Crohn Disease Graham, Emily Rao, Krishna Cinti, Sandro Infect Dis (Auckl) Original Research BACKGROUND: Few studies exist to guide the treatment approach to intra-abdominal abscesses in Crohn disease, which can include antimicrobials alone or in conjunction with percutaneous drainage or surgery. The primary aim of this study is to review outcomes from different treatment approaches to intra-abdominal abscess in Crohn disease. METHODS: Medical records were reviewed for patients admitted to the University of Michigan health care system with Crohn disease and intra-abdominal abscess over a 4-year period. Outcomes were compared among medical and interventional approaches. The χ(2) test was used to test for statistical significance. RESULTS: Of the 33 patients included, 13 were in the medical group and 20 were in the interventional group. Abscess recurrence/nonresolution occurred in 31% of patients in the medical group and 25% of patients in the interventional group (P = .7). CONCLUSIONS: In this study, there was no significant difference in outcome between medical and interventional therapy for intra-abdominal abscess in Crohn disease. SAGE Publications 2017-04-07 /pmc/articles/PMC5398645/ /pubmed/28469460 http://dx.doi.org/10.1177/1179916117701736 Text en © The Author(s) 2017 http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page(https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Original Research
Graham, Emily
Rao, Krishna
Cinti, Sandro
Medical Versus Interventional Treatment of Intra-Abdominal Abscess in Patients With Crohn Disease
title Medical Versus Interventional Treatment of Intra-Abdominal Abscess in Patients With Crohn Disease
title_full Medical Versus Interventional Treatment of Intra-Abdominal Abscess in Patients With Crohn Disease
title_fullStr Medical Versus Interventional Treatment of Intra-Abdominal Abscess in Patients With Crohn Disease
title_full_unstemmed Medical Versus Interventional Treatment of Intra-Abdominal Abscess in Patients With Crohn Disease
title_short Medical Versus Interventional Treatment of Intra-Abdominal Abscess in Patients With Crohn Disease
title_sort medical versus interventional treatment of intra-abdominal abscess in patients with crohn disease
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398645/
https://www.ncbi.nlm.nih.gov/pubmed/28469460
http://dx.doi.org/10.1177/1179916117701736
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