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Mice expressing a “hyper-sensitive” form of the CB(1) cannabinoid receptor (CB(1)) show modestly enhanced alcohol preference and consumption

We recently characterized S426A/S430A mutant mice expressing a desensitization-resistant form of the CB(1) receptor. These mice display an enhanced response to endocannabinoids and ∆(9)-THC. In this study, S426A/S430A mutants were used as a novel model to test whether ethanol consumption, morphine d...

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Detalles Bibliográficos
Autores principales:	Marcus, David J., Henderson-Redmond, Angela N., Gonek, Maciej, Zee, Michael L., Farnsworth, Jill C., Amin, Randa A., Andrews, Mary-Jeanette, Davis, Brian J., Mackie, Ken, Morgan, Daniel J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398885/ https://www.ncbi.nlm.nih.gov/pubmed/28426670 http://dx.doi.org/10.1371/journal.pone.0174826

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