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Hippo signaling governs cytosolic nucleic acid sensing through YAP/TAZ-mediated TBK1 blockade
The Hippo pathway senses cellular conditions and regulates YAP/TAZ to control cellular and tissue homeostasis, while TBK1 is central for cytosolic nucleic acid sensing and antiviral defense. The correlation between cellular nutrient/physical status and host antiviral defense is interesting but not w...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398908/ https://www.ncbi.nlm.nih.gov/pubmed/28346439 http://dx.doi.org/10.1038/ncb3496 |