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MMTV-cre;Ccn6 knockout mice develop tumors recapitulating human metaplastic breast carcinomas

Metaplastic breast carcinoma is an aggressive form of invasive breast cancer with histological evidence of epithelial to mesenchymal transition (EMT). However, the defining molecular events are unknown. Here we show that CCN6 (WISP3), a secreted matricellular protein of the CCN (CYR61/CTGF/NOV) fami...

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Detalles Bibliográficos
Autores principales:	Martin, Emily E., Huang, Wei, Anwar, Talha, Arellano-Garcia, Caroline, Burman, Boris, Guan, Jun-Lin, Gonzalez, Maria E., Kleer, Celina G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398917/ https://www.ncbi.nlm.nih.gov/pubmed/27819674 http://dx.doi.org/10.1038/onc.2016.381

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