Cargando…

Human Cytomegalovirus-Induced Degradation of CYTIP Modulates Dendritic Cell Adhesion and Migration

As potent antigen-presenting cells, dendritic cells (DCs) are essential for the initiation of effective antiviral immune responses. Viruses and especially herpesviruses, which are able to establish lifelong persistence, exploit several immune evasion mechanisms targeting DC biology. Our group has pr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Grosche, Linda, Draßner, Christina, Mühl-Zürbes, Petra, Kamm, Lisa, Le-Trilling, Vu Thuy Khanh, Trilling, Mirko, Steinkasserer, Alexander, Heilingloh, Christiane S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399032/ https://www.ncbi.nlm.nih.gov/pubmed/28484459 http://dx.doi.org/10.3389/fimmu.2017.00461

Ejemplares similares

The Major Immediate-Early Protein IE2 of Human Cytomegalovirus Is Sufficient to Induce Proteasomal Degradation of CD83 on Mature Dendritic Cells
por: Heilingloh, Christiane S., et al.
Publicado: (2017)

Herpes Simplex Virus Type-2 Paralyzes the Function of Monocyte-Derived Dendritic Cells
por: Grosche, Linda, et al.
Publicado: (2020)

HSV-1 Modulates IL-6 Receptor Expression on Human Dendritic Cells
por: Birzer, Alexandra, et al.
Publicado: (2020)

Autophagic degradation of lamins facilitates the nuclear egress of herpes simplex virus type 1
por: Turan, Aykut, et al.
Publicado: (2019)

Mouse newborn cells allow highly productive mouse cytomegalovirus replication, constituting a novel convenient primary cell culture system
por: Le-Trilling, Vu Thuy Khanh, et al.
Publicado: (2017)

Cellular Cullin RING Ubiquitin Ligases: Druggable Host Dependency Factors of Cytomegaloviruses
por: Becker, Tanja, et al.
Publicado: (2019)

In Human Monocyte Derived Dendritic Cells SOCS1 Interacting with CYTIP Induces the Degradation of CYTIP by the Proteasome
por: Grabher, Daniela, et al.
Publicado: (2013)

Mouse Cytomegalovirus M34 Encodes a Non-essential, Nuclear, Early-Late Expressed Protein Required for Efficient Viral Replication
por: Eilbrecht, Mareike, et al.
Publicado: (2020)

Mass Spectrometric Characterization of HSV-1 L-Particles From Human Dendritic Cells and BHK21 Cells and Analysis of Their Functional Role
por: Birzer, Alexandra, et al.
Publicado: (2020)

Nedd8-Activating Enzyme Is a Druggable Host Dependency Factor of Human and Mouse Cytomegalovirus
por: Flores-Martínez, Yulia Alejandra, et al.
Publicado: (2021)

Deletion of the non-adjacent genes UL148 and UL148D impairs human cytomegalovirus-mediated TNF receptor 2 surface upregulation
por: Le-Trilling, Vu Thuy Khanh, et al.
Publicado: (2023)

Cytip regulates dendritic-cell function in contact hypersensitivity
por: Heib, Valeska, et al.
Publicado: (2012)

A simple algorithm based on initial Ct values predicts the duration to SARS-CoV-2 negativity and allows more efficient test-to-release and return-to-work schedules
por: Anastasiou, Olympia E., et al.
Publicado: (2023)

The Transcription and Translation Landscapes during Human Cytomegalovirus Infection Reveal Novel Host-Pathogen Interactions
por: Tirosh, Osnat, et al.
Publicado: (2015)

Identification of DNA-Damage DNA-Binding Protein 1 as a Conditional Essential Factor for Cytomegalovirus Replication in Interferon-γ-Stimulated Cells
por: Trilling, Mirko, et al.
Publicado: (2011)

Immunization with a murine cytomegalovirus based vector encoding retrovirus envelope confers strong protection from Friend retrovirus challenge infection
por: Bongard, Nadine, et al.
Publicado: (2019)

Establishment and clinical validation of an in-cell-ELISA-based assay for the rapid quantification of Rabies lyssavirus neutralizing antibodies
por: Schöler, Lara, et al.
Publicado: (2022)

Maternal antibodies induced by a live attenuated vaccine protect neonatal mice from cytomegalovirus
por: Le-Trilling, Vu Thuy Khanh, et al.
Publicado: (2023)

Deciphering of the Human Interferon-Regulated Proteome by Mass Spectrometry-Based Quantitative Analysis Reveals Extent and Dynamics of Protein Induction and Repression
por: Megger, Dominik A., et al.
Publicado: (2017)

HLA-B locus products resist degradation by the human cytomegalovirus immunoevasin US11
por: Zimmermann, Cosima, et al.
Publicado: (2019)

What Goes Around, Comes Around – HSV-1 Replication in Monocyte-Derived Dendritic Cells
por: Grosche, Linda, et al.
Publicado: (2017)

Exploitation of Herpesviral Transactivation Allows Quantitative Reporter Gene-Based Assessment of Virus Entry and Neutralization
por: Reinhard, Henrike, et al.
Publicado: (2011)

STAT2-Dependent Immune Responses Ensure Host Survival despite the Presence of a Potent Viral Antagonist
por: Le-Trilling, Vu Thuy Khanh, et al.
Publicado: (2018)

Over 90% of clinical swabs used for SARS‐CoV‐2 diagnostics contain sufficient nucleic acid concentrations
por: Klingen, Robin L., et al.
Publicado: (2021)

The Donor Major Histocompatibility Complex Class I Chain-Related Molecule A Allele rs2596538 G Predicts Cytomegalovirus Viremia in Kidney Transplant Recipients
por: Rohn, Hana, et al.
Publicado: (2018)

Turmeric Root and Its Bioactive Ingredient Curcumin Effectively Neutralize SARS-CoV-2 In Vitro
por: Bormann, Maren, et al.
Publicado: (2021)

CD83 expressed by macrophages is an important immune checkpoint molecule for the resolution of inflammation
por: Peckert-Maier, Katrin, et al.
Publicado: (2023)

A Novel In-Cell ELISA Assay Allows Rapid and Automated Quantification of SARS-CoV-2 to Analyze Neutralizing Antibodies and Antiviral Compounds
por: Schöler, Lara, et al.
Publicado: (2020)

The human cytomegalovirus protein UL147A downregulates the most prevalent MICA allele: MICA*008, to evade NK cell-mediated killing
por: Seidel, Einat, et al.
Publicado: (2021)

Human cytomegalovirus antagonizes activation of Fcγ receptors by distinct and synergizing modes of IgG manipulation
por: Kolb, Philipp, et al.
Publicado: (2021)

Discrepancy between frequent occurrence of COVID‐19‐like symptoms and low seroconversion rates among healthcare workers
por: Dehnen, Dorothea, et al.
Publicado: (2021)

Human Cytomegalovirus Fcγ Binding Proteins gp34 and gp68 Antagonize Fcγ Receptors I, II and III
por: Corrales-Aguilar, Eugenia, et al.
Publicado: (2014)

Opposing Development of Cytotoxic and Follicular Helper CD4 T Cells Controlled by the TCF-1-Bcl6 Nexus
por: Donnarumma, Tiziano, et al.
Publicado: (2016)

A rapid test recognizing mucosal SARS-CoV-2-specific antibodies distinguishes prodromal from convalescent COVID-19
por: Krempe, Friederike, et al.
Publicado: (2021)

What the HEC happens around the heart during COVID-19?
por: Trilling, Mirko
Publicado: (2021)

Broad and potent antiviral activity of the NAE inhibitor MLN4924
por: Le-Trilling, Vu Thuy Khanh, et al.
Publicado: (2016)

Antibody responses elicited by mRNA vaccination in firefighters persist six months and correlate inversely with age and directly with BMI
por: Holtkamp, Caroline, et al.
Publicado: (2022)

Herpes Simplex Virus Type 2 Is More Difficult to Neutralize by Antibodies Than Herpes Simplex Virus Type 1
por: Silke Heilingloh, Christiane, et al.
Publicado: (2020)

Structural mechanism of CRL4‐instructed STAT2 degradation via a novel cytomegaloviral DCAF receptor
por: Le‐Trilling, Vu Thuy Khanh, et al.
Publicado: (2023)

A Mass Spectrometry-Based Profiling of Interactomes of Viral DDB1- and Cullin Ubiquitin Ligase-Binding Proteins Reveals NF-κB Inhibitory Activity of the HIV-2-Encoded Vpx
por: Landsberg, Christine D., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_oka96qan5is931lrrvr2r6ts5b