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Impact of pe_pgrs33 Gene Polymorphisms on Mycobacterium tuberculosis Infection and Pathogenesis

PE_PGRS33 is a surface-exposed protein of Mycobacterium tuberculosis (Mtb) which exerts its role in macrophages entry and immunomodulation. In this study, we aimed to investigate the polymorphisms in the pe_pgrs33 gene of Mtb clinical isolates and evaluate their impact on protein functions. We seque...

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Detalles Bibliográficos
Autores principales: Camassa, Serena, Palucci, Ivana, Iantomasi, Raffaella, Cubeddu, Tiziana, Minerva, Mariachiara, De Maio, Flavio, Jouny, Samuel, Petruccioli, Elisa, Goletti, Delia, Ria, Francesco, Sali, Michela, Sanguinetti, Maurizio, Manganelli, Riccardo, Rocca, Stefano, Brodin, Priscille, Delogu, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399086/
https://www.ncbi.nlm.nih.gov/pubmed/28484686
http://dx.doi.org/10.3389/fcimb.2017.00137