Cargando…
Rationale, design and critical end points for the Riluzole in Acute Spinal Cord Injury Study (RISCIS): a randomized, double-blinded, placebo-controlled parallel multi-center trial
BACKGROUND: Riluzole is a sodium channel-blocking agent used in treating amyotrophic lateral sclerosis. It has been approved by the U.S. Food and Drug Administration, Canadian and Australian authorities, and in many other countries. A phase I trial of riluzole for acute spinal cord injury (SCI) prov...
Autores principales: | Fehlings, M G, Nakashima, H, Nagoshi, N, Chow, D S L, Grossman, R G, Kopjar, B |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399137/ https://www.ncbi.nlm.nih.gov/pubmed/26099215 http://dx.doi.org/10.1038/sc.2015.95 |
Ejemplares similares
-
Riluzole as a Neuroprotective Drug for Spinal Cord Injury: From Bench to Bedside
por: Nagoshi, Narihito, et al.
Publicado: (2015) -
Evaluation of the sodium-glutamate blocker riluzole in a preclinical model of ervical spinal cord injury
por: Wu, Yongchao, et al.
Publicado: (2010) -
Longitudinal Impact of Acute Spinal Cord Injury on Clinical Pharmacokinetics of Riluzole, a Potential Neuroprotective Agent
por: Nguyen, Ashley, et al.
Publicado: (2021) -
A Randomized, Double Blind, Placebo-Controlled Trial of Pioglitazone in Combination with Riluzole in Amyotrophic Lateral Sclerosis
por: Dupuis, Luc, et al.
Publicado: (2012) -
The Impact of Riluzole on Neurobehavioral Outcomes in Preclinical Models of Traumatic and Nontraumatic Spinal Cord Injury: Results From a Systematic Review of the Literature
por: Tetreault, Lindsay A., et al.
Publicado: (2019)